SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gxa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 7 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.01A 1rxcF-2gxaA:
undetectable		 1rxcF-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 7 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.04A 1rxcL-2gxaA:
undetectable		 1rxcL-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		3 / 3 GLU A 529
GLN A 527
ARG A 543
 None
 0.76A 2w3bB-2gxaA:
undetectable		 2w3bB-2gxaA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		3 / 3 SER A 522
THR A 437
PHE A 402
 None
ADP  A   1 (-4.5A)
None
 0.66A 2x91A-2gxaA:
undetectable		 2x91A-2gxaA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.05A 3kvvA-2gxaA:
undetectable		 3kvvA-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.05A 3kvvB-2gxaA:
undetectable		 3kvvB-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.08A 3kvvC-2gxaA:
undetectable		 3kvvC-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.02A 3kvvD-2gxaA:
undetectable		 3kvvD-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.02A 3kvvE-2gxaA:
undetectable		 3kvvE-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.06A 3kvvF-2gxaA:
undetectable		 3kvvF-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 5 PHE A 311
GLY A 314
CYH A 361
HIS A 357
 None
 1.17A 3r0lD-2gxaA:
undetectable		 3r0lD-2gxaA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 8 TRP A 564
PHE A 568
PRO A 517
TRP A 419
 None
 1.17A 3v35A-2gxaA:
undetectable		 3v35A-2gxaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 8 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 0.97A 4e1vA-2gxaA:
undetectable		 4e1vA-2gxaA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 7 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.04A 4e1vB-2gxaA:
undetectable		 4e1vB-2gxaA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 6 GLN A 374
ARG A 370
ILE A 503
VAL A 511
 None
 1.05A 4e1vF-2gxaA:
undetectable		 4e1vF-2gxaA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2gxa REPLICATION PROTEIN
E1
(Deltapapillomavi
rus
4) 		4 / 8 LEU A 535
LEU A 496
ILE A 524
VAL A 477
 None
 0.82A 4klaA-2gxaA:
undetectable		 4klaA-2gxaA:
21.41