SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gz4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 2gz4 HYPOTHETICAL PROTEIN
ATU1052
(Agrobacterium
fabrum) 		4 / 6 VAL A  56
THR A  55
LEU A  38
ARG A  40
 None
 0.91A 1s8fB-2gz4A:
undetectable		 1s8fB-2gz4A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2gz4 HYPOTHETICAL PROTEIN
ATU1052
(Agrobacterium
fabrum) 		4 / 5 ARG A  40
THR A 182
LEU A 179
ALA A  39
 None
 1.45A 2e1qD-2gz4A:
undetectable		 2e1qD-2gz4A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2gz4 HYPOTHETICAL PROTEIN
ATU1052
(Agrobacterium
fabrum) 		5 / 12 ASP A  77
GLU A  78
HIS A 119
ALA A 128
ARG A 135
 None
 1.15A 5nd4B-2gz4A:
undetectable		 5nd4B-2gz4A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 2gz4 HYPOTHETICAL PROTEIN
ATU1052
(Agrobacterium
fabrum) 		3 / 3 THR A  65
PRO A 166
ARG A 167
 None
 0.65A 5nd7B-2gz4A:
undetectable		 5nd7B-2gz4A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2gz4 HYPOTHETICAL PROTEIN
ATU1052
(Agrobacterium
fabrum) 		3 / 3 GLY A 123
ASP A  77
ILE A 195
 None
 0.51A 6dgxB-2gz4A:
undetectable		 6dgxB-2gz4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2gz4 HYPOTHETICAL PROTEIN
ATU1052
(Agrobacterium
fabrum) 		4 / 7 ASP A 140
ARG A  43
GLU A  89
ASP A  94
 None
 1.24A 6mn5E-2gz4A:
undetectable		 6mn5E-2gz4A:
18.23