SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		5 / 12 LEU A   5
LEU A   8
LEU A  11
LEU A 313
TYR A 317
 None
 0.91A 1sqnB-2gz6A:
undetectable		 1sqnB-2gz6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		5 / 12 LEU A 307
LEU A 310
LEU A 313
ALA A 314
LEU A  11
 None
 0.89A 1ya3C-2gz6A:
undetectable		 1ya3C-2gz6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		5 / 12 MET A 315
GLU A 242
VAL A 201
ASP A 249
ILE A 250
 None
 1.21A 3jayA-2gz6A:
undetectable		 3jayA-2gz6A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		5 / 10 ARG A 375
GLY A 238
VAL A 305
GLU A 308
ASN A 236
 None
 1.30A 3uayA-2gz6A:
undetectable		 3uayA-2gz6A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		4 / 7 ASN A  18
GLN A   6
TYR A  12
PRO A  22
 None
 1.23A 3ugrA-2gz6A:
undetectable		 3ugrA-2gz6A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		3 / 3 ASN A 179
GLU A 183
ARG A 375
 None
 1.09A 3wxoA-2gz6A:
undetectable		 3wxoA-2gz6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		6 / 12 GLY A 316
ILE A 270
ILE A 247
ARG A 322
ILE A 250
THR A 259
 None
 1.40A 4q5mA-2gz6A:
undetectable		 4q5mA-2gz6A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		4 / 6 GLY A 232
GLU A 231
ASP A 287
ASP A 210
 None
 0.96A 4uckB-2gz6A:
undetectable		 4uckB-2gz6A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		3 / 3 PHE A  36
ASP A  49
LEU A 360
 None
 0.78A 5uhbC-2gz6A:
undetectable		 5uhbC-2gz6A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		4 / 7 GLY A 364
TYR A 284
TRP A 303
ASP A  47
 None
 0.97A 5vlmE-2gz6A:
1.4		 5vlmE-2gz6A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		4 / 4 GLY A  43
ASP A  40
ARG A  41
MET A 377
 None
 1.24A 5zrfA-2gz6A:
0.0		 5zrfA-2gz6A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 2gz6 N-ACETYL-D-GLUCOSAMI
NE 2-EPIMERASE
(Anabaena
sp.
CH1) 		3 / 3 TYR A  12
HIS A 333
MET A 332
 None
 1.16A 6af6A-2gz6A:
undetectable		 6af6A-2gz6A:
21.43