SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gzb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.09A 1p7lC-2gzbA:
undetectable		 1p7lC-2gzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.09A 1p7lD-2gzbA:
undetectable		 1p7lD-2gzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.09A 1rg9A-2gzbA:
undetectable		 1rg9A-2gzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.08A 1rg9B-2gzbA:
undetectable		 1rg9B-2gzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.08A 1rg9C-2gzbA:
undetectable		 1rg9C-2gzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.08A 1rg9D-2gzbA:
undetectable		 1rg9D-2gzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		5 / 12 HIS A  50
GLY A  29
VAL A  45
ASP A  47
PHE A  77
 None
 0.99A 2f8lA-2gzbA:
undetectable		 2f8lA-2gzbA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.03A 2obvA-2gzbA:
undetectable		 2obvA-2gzbA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.08A 2p02A-2gzbA:
undetectable		 2p02A-2gzbA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		5 / 12 VAL A   2
ILE A   3
ILE A  67
VAL A  11
PRO A  10
 None
 0.94A 3kpdC-2gzbA:
undetectable		 3kpdC-2gzbA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 7 ILE A 122
GLU A  85
THR A 102
VAL A  44
 None
 0.77A 3ua5B-2gzbA:
undetectable		 3ua5B-2gzbA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.05A 4kttA-2gzbA:
undetectable		 4kttA-2gzbA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.05A 4kttC-2gzbA:
undetectable		 4kttC-2gzbA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.08A 4ndnA-2gzbA:
undetectable		 4ndnA-2gzbA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 7 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.09A 4ndnC-2gzbA:
undetectable		 4ndnC-2gzbA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 7 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.08A 4odjA-2gzbA:
undetectable		 4odjA-2gzbA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.03A 5a1iA-2gzbA:
undetectable		 5a1iA-2gzbA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 7 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.03A 5a1iA-2gzbA:
undetectable		 5a1iA-2gzbA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		5 / 12 SER A 106
THR A 102
GLY A 109
PRO A 110
PHE A 111
 None
 0.89A 5jo9A-2gzbA:
undetectable		 5jo9A-2gzbA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 5 VAL A  45
ASP A  47
PRO A  48
ALA A  31
 None
 1.14A 5otrA-2gzbA:
undetectable		 5otrA-2gzbA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.03A 5t8sB-2gzbA:
undetectable		 5t8sB-2gzbA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 LEU A 146
VAL A  99
VAL A  44
ILE A  75
 None
 0.67A 5y9mA-2gzbA:
undetectable		 5y9mA-2gzbA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 LEU A 146
VAL A  99
VAL A  44
ILE A  75
 None
 0.67A 5y9mX-2gzbA:
undetectable		 5y9mX-2gzbA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.13A 6fbnB-2gzbA:
undetectable		 6fbnB-2gzbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.02A 6fboA-2gzbA:
undetectable		 6fboA-2gzbA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.09A 6fcbA-2gzbA:
undetectable		 6fcbA-2gzbA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 8 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.00A 6fcdA-2gzbA:
undetectable		 6fcdA-2gzbA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI
(Bauhinia
bauhinioides) 		4 / 7 HIS A  49
PRO A  48
ASP A  47
ASP A 142
 None
 1.02A 6g6rA-2gzbA:
undetectable		 6g6rA-2gzbA:
18.35