SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gzq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 2gzq PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Plasmodium
vivax) 		3 / 3 ASP A  90
PHE A  74
VAL A 173
 None
 0.78A 1kijB-2gzqA:
undetectable		 1kijB-2gzqA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 2gzq PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Plasmodium
vivax) 		5 / 11 ILE A 135
ILE A 181
ASP A  90
LEU A  10
PHE A 184
 None
 1.20A 2azyA-2gzqA:
undetectable		 2azyA-2gzqA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 2gzq PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Plasmodium
vivax) 		4 / 4 PRO A  56
TYR A 118
GLY A 107
THR A 108
 None
 0.97A 3ib0A-2gzqA:
undetectable		 3ib0A-2gzqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 2gzq PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Plasmodium
vivax) 		4 / 5 PHE A  74
ILE A  59
ASN A 143
PHE A 134
 None
 1.10A 3octA-2gzqA:
undetectable		 3octA-2gzqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2gzq PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Plasmodium
vivax) 		4 / 5 GLY A 145
ILE A 113
VAL A 139
SER A  97
 None
 1.27A 4d33A-2gzqA:
undetectable		 4d33A-2gzqA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 2gzq PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Plasmodium
vivax) 		5 / 10 MET A  31
LEU A  27
VAL A  19
ILE A 174
PRO A  78
 None
 1.18A 5ienB-2gzqA:
undetectable		 5ienB-2gzqA:
22.61