SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YNN_C_RFPC1120_1 (DNA-DIRECTED RNA POLYMERASE BETA CHAIN)	2h01	2-CYS PEROXIREDOXIN (Plasmodium yoelii)	5 / 12	ASP A 71 HIS A 76 LEU A 51 PRO A 45 ILE A 48	None	1.20A	1ynnC-2h01A: 0.7	1ynnC-2h01A: 10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KMU_H_RFPH1401_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	2h01	2-CYS PEROXIREDOXIN (Plasmodium yoelii)	5 / 12	ASP A 71 HIS A 76 LEU A 51 PRO A 45 ILE A 48	None	1.27A	4kmuH-2h01A: 0.0	4kmuH-2h01A: 11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R38_D_RBFD201_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	2h01	2-CYS PEROXIREDOXIN (Plasmodium yoelii)	4 / 8	ILE A 147 LEU A 22 ILE A 97 PHE A 121	None	0.86A	4r38D-2h01A: undetectable	4r38D-2h01A: 21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAC_C_RFPC3001_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	2h01	2-CYS PEROXIREDOXIN (Plasmodium yoelii)	5 / 12	ASP A 71 HIS A 76 LEU A 51 PRO A 45 ILE A 48	None	1.39A	5uacC-2h01A: 0.0	5uacC-2h01A: 11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB307_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	2h01	2-CYS PEROXIREDOXIN (Plasmodium yoelii)	3 / 3	LEU A 154 ALA A 153 LEU A 123	None	0.50A	5uunB-2h01A: undetectable	5uunB-2h01A: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2h01	2-CYS PEROXIREDOXIN (Plasmodium yoelii)	3 / 3	ARG A 106 LEU A 111 PHE A 112	None	0.74A	6nknP-2h01A: undetectable	6nknP-2h01A: 18.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YNN_C_RFPC1120_1","DNA-DIRECTED RNA POLYMERASE BETA CHAIN","2h01","2-CYS PEROXIREDOXIN","Plasmodium yoelii",5,"ASP A  71;HIS A  76;LEU A  51;PRO A  45;ILE A  48","None","1.20A","1ynnC-2h01A:0.7","1ynnC-2h01A:10.08"],["4KMU_H_RFPH1401_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","2h01","2-CYS PEROXIREDOXIN","Plasmodium yoelii",5,"ASP A  71;HIS A  76;LEU A  51;PRO A  45;ILE A  48","None","1.27A","4kmuH-2h01A:0.0","4kmuH-2h01A:11.47"],["4R38_D_RBFD201_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","2h01","2-CYS PEROXIREDOXIN","Plasmodium yoelii",4,"ILE A 147;LEU A  22;ILE A  97;PHE A 121","None","0.86A","4r38D-2h01A:undetectable","4r38D-2h01A:21.00"],["5UAC_C_RFPC3001_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","2h01","2-CYS PEROXIREDOXIN","Plasmodium yoelii",5,"ASP A  71;HIS A  76;LEU A  51;PRO A  45;ILE A  48","None","1.39A","5uacC-2h01A:0.0","5uacC-2h01A:11.47"],["5UUN_B_ACTB307_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","2h01","2-CYS PEROXIREDOXIN","Plasmodium yoelii",3,"LEU A 154;ALA A 153;LEU A 123","None","0.50A","5uunB-2h01A:undetectable","5uunB-2h01A:22.07"],["6NKN_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2h01","2-CYS PEROXIREDOXIN","Plasmodium yoelii",3,"ARG A 106;LEU A 111;PHE A 112","None","0.74A","6nknP-2h01A:undetectable","6nknP-2h01A:18.39"]]