SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 VAL A 437
ASN A 318
GLY A 443
LEU A 445
 None
 0.84A 1dzmA-2h0bA:
undetectable		 1dzmA-2h0bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 GLY A 349
GLY A 347
ILE A 344
LEU A 320
PRO A 436
 None
CA  A1000 ( 4.4A)
None
None
None
 1.02A 1p91B-2h0bA:
undetectable		 1p91B-2h0bA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 LEU A 342
ILE A 344
LEU A 346
TYR A 330
GLY A 349
 None
 1.32A 2bxmA-2h0bA:
undetectable		 2bxmA-2h0bA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 ARG A 377
GLN A 302
PRO A 300
ILE A 344
PRO A 433
 None
 1.31A 3ganA-2h0bA:
undetectable		 3ganA-2h0bA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 LEU A 320
LEU A 322
VAL A 340
SER A 341
 None
 0.97A 4qknA-2h0bA:
undetectable		 4qknA-2h0bA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 5 LEU A 457
VAL A 423
VAL A 331
TYR A 294
 None
 1.11A 4r7iA-2h0bA:
undetectable		 4r7iA-2h0bA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 TRP A 367
GLU A 281
ASP A 369
 None
 0.98A 5gqbA-2h0bA:
undetectable		 5gqbA-2h0bA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 2h0b NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 THR A 324
ASP A 419
LEU A 296
ASP A 295
 None
 1.20A 5tdzA-2h0bA:
undetectable		 5tdzA-2h0bA:
19.66