SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P9G_A_ACTA42_0 (EAFP 2)	2h0d	B LYMPHOMA MO-MLV INSERTION REGION UBIQUITIN LIGASE PROTEIN RING2 (Homo sapiens; Homo sapiens)	3 / 3	CYH A 42 ARG B 26 CYH A 21	ZN A 201 (-2.3A) ZN A 201 ( 4.5A) ZN A 201 (-2.3A)	1.49A	1p9gA-2h0dA: undetectable	1p9gA-2h0dA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_F_SNLF6001_2 (MINERALOCORTICOID RECEPTOR)	2h0d	B LYMPHOMA MO-MLV INSERTION REGION UBIQUITIN LIGASE PROTEIN RING2 (Homo sapiens)	4 / 5	LEU A 12 LEU A 82 LEU B 45 MET B 50	None	1.09A	2oaxF-2h0dA: undetectable	2oaxF-2h0dA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2h0d	UBIQUITIN LIGASE PROTEIN RING2 (Homo sapiens)	4 / 5	LEU B 100 CYH B 51 LEU B 58 ASP B 103	None ZN B 203 (-2.3A) None None	1.22A	5mafA-2h0dB: undetectable	5mafA-2h0dB: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_A_RFPA502_2 (RIFAMPIN MONOOXYGENASE)	2h0d	B LYMPHOMA MO-MLV INSERTION REGION UBIQUITIN LIGASE PROTEIN RING2 (Homo sapiens)	4 / 4	GLN B 29 VAL A 79 ARG A 45 ARG A 93	None	0.97A	6brdA-2h0dB: undetectable	6brdA-2h0dB: 18.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P9G_A_ACTA42_0","EAFP 2","2h0d","B LYMPHOMA MO-MLV INSERTION REGION;UBIQUITIN LIGASE PROTEIN RING2","Homo sapiens;Homo sapiens",3,"CYH A  42;ARG B  26;CYH A  21"," ZN A 201 (-2.3A); ZN A 201 ( 4.5A); ZN A 201 (-2.3A)","1.49A","1p9gA-2h0dA:undetectable","1p9gA-2h0dA:13.33"],["2OAX_F_SNLF6001_2","MINERALOCORTICOID RECEPTOR","2h0d","B LYMPHOMA MO-MLV INSERTION REGION;UBIQUITIN LIGASE PROTEIN RING2","Homo sapiens",4,"LEU A  12;LEU A  82;LEU B  45;MET B  50","None","1.09A","2oaxF-2h0dA:undetectable","2oaxF-2h0dA:15.73"],["5MAF_A_XINA403_2","MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE","2h0d","UBIQUITIN LIGASE PROTEIN RING2","Homo sapiens",4,"LEU B 100;CYH B  51;LEU B  58;ASP B 103","None; ZN B 203 (-2.3A);None;None","1.22A","5mafA-2h0dB:undetectable","5mafA-2h0dB:25.00"],["6BRD_A_RFPA502_2","RIFAMPIN MONOOXYGENASE","2h0d","B LYMPHOMA MO-MLV INSERTION REGION;UBIQUITIN LIGASE PROTEIN RING2","Homo sapiens",4,"GLN B  29;VAL A  79;ARG A  45;ARG A  93","None","0.97A","6brdA-2h0dB:undetectable","6brdA-2h0dB:18.18"]]