SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h0e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_0 (WNT INHIBITORY FACTOR 1)	2h0e	TRANSTHYRETIN-LIKE PROTEIN PUCM (Bacillus subtilis)	5 / 12	ILE A 29 LEU A 54 MET A 67 PHE A 69 VAL A 117	None	0.98A	2ygnA-2h0eA: undetectable	2ygnA-2h0eA: 19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGQ_A_PCFA1275_0 (WNT INHIBITORY FACTOR 1)	2h0e	TRANSTHYRETIN-LIKE PROTEIN PUCM (Bacillus subtilis)	6 / 12	ILE A 29 LEU A 54 ILE A 15 MET A 67 PHE A 69 PHE A 95	None	1.10A	2ygqA-2h0eA: undetectable	2ygqA-2h0eA: 15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0Q_A_PX9A201_0 (BETA-LACTOGLOBULIN)	2h0e	TRANSTHYRETIN-LIKE PROTEIN PUCM (Bacillus subtilis)	5 / 12	VAL A 93 VAL A 91 LEU A 110 PHE A 69 MET A 67	None	1.11A	4y0qA-2h0eA: undetectable	4y0qA-2h0eA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CDP_H_EVPH2101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B)	2h0e	TRANSTHYRETIN-LIKE PROTEIN PUCM (Bacillus subtilis)	4 / 6	GLU A 36 GLY A 9 ASP A 101 GLY A 57	None	0.97A	5cdpA-2h0eA: undetectable 5cdpB-2h0eA: undetectable	5cdpA-2h0eA: 13.89 5cdpB-2h0eA: 23.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGN_A_PCFA1179_0","WNT INHIBITORY FACTOR 1","2h0e","TRANSTHYRETIN-LIKE PROTEIN PUCM","Bacillus subtilis",5,"ILE A  29;LEU A  54;MET A  67;PHE A  69;VAL A 117","None","0.98A","2ygnA-2h0eA:undetectable","2ygnA-2h0eA:19.64"],["2YGQ_A_PCFA1275_0","WNT INHIBITORY FACTOR 1","2h0e","TRANSTHYRETIN-LIKE PROTEIN PUCM","Bacillus subtilis",6,"ILE A  29;LEU A  54;ILE A  15;MET A  67;PHE A  69;PHE A  95","None","1.10A","2ygqA-2h0eA:undetectable","2ygqA-2h0eA:15.65"],["4Y0Q_A_PX9A201_0","BETA-LACTOGLOBULIN","2h0e","TRANSTHYRETIN-LIKE PROTEIN PUCM","Bacillus subtilis",5,"VAL A  93;VAL A  91;LEU A 110;PHE A  69;MET A  67","None","1.11A","4y0qA-2h0eA:undetectable","4y0qA-2h0eA:20.25"],["5CDP_H_EVPH2101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B","2h0e","TRANSTHYRETIN-LIKE PROTEIN PUCM","Bacillus subtilis",4,"GLU A  36;GLY A   9;ASP A 101;GLY A  57","None","0.97A","5cdpA-2h0eA:undetectable;5cdpB-2h0eA:undetectable","5cdpA-2h0eA:13.89;5cdpB-2h0eA:23.50"]]