SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 5 THR A  32
GLU A  27
THR A  90
LEU A  10
 None
 1.38A 1d4fC-2h1rA:
3.6		 1d4fC-2h1rA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ILE A  28
GLY A  29
GLY A  31
ASN A  92
PRO A  94
 None
 1.05A 1nv8A-2h1rA:
10.8		 1nv8A-2h1rA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 GLU A  27
GLY A  29
GLY A  31
ILE A  51
ILE A  97
 None
 0.78A 1qaoA-2h1rA:
21.0		 1qaoA-2h1rA:
28.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		6 / 12 GLY A  29
GLY A  31
ASN A  92
PRO A  94
ILE A  97
PHE A 160
 None
 0.75A 1zq9B-2h1rA:
33.7		 1zq9B-2h1rA:
44.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 VAL A 131
TYR A 136
ILE A 141
ASP A 260
 None
 1.24A 2x45B-2h1rA:
undetectable		 2x45B-2h1rA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 VAL A 131
TYR A 136
ILE A 141
ASP A 260
 None
 1.25A 2x45C-2h1rA:
undetectable		 2x45C-2h1rA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 VAL A 131
TYR A 136
ILE A 141
ASP A 260
 None
 1.22A 3bu1A-2h1rA:
undetectable		 3bu1A-2h1rA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 GLY A  29
LEU A  35
ASP A  50
ILE A  51
ASP A  52
 None
 0.97A 3cjtC-2h1rA:
14.0		 3cjtC-2h1rA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 CYH A  89
PHE A 112
PHE A  86
 None
 1.04A 3cr5X-2h1rA:
0.0		 3cr5X-2h1rA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 11 GLU A  27
GLY A  29
GLY A  31
ILE A  49
ALA A  78
 None
 0.88A 3dxyA-2h1rA:
9.8		 3dxyA-2h1rA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 CYH A  30
LEU A  71
VAL A  73
ILE A  49
LEU A  10
 None
 1.29A 3g9eA-2h1rA:
undetectable		 3g9eA-2h1rA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 GLY A  29
CYH A  30
LEU A  71
VAL A  73
ILE A  49
 None
 1.19A 3g9eA-2h1rA:
undetectable		 3g9eA-2h1rA:
21.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 11 GLY A  29
GLY A  31
ILE A  51
ASP A  52
ALA A  78
 None
 0.69A 3grvA-2h1rA:
26.1		 3grvA-2h1rA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		6 / 12 LEU A   4
GLU A  27
GLY A  29
GLY A  31
ASP A  52
ASN A  92
 None
 0.83A 3gryA-2h1rA:
26.2		 3gryA-2h1rA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		7 / 12 LEU A   4
GLU A  27
GLY A  29
GLY A  31
ILE A  51
ASP A  52
ALA A  78
 None
 0.90A 3gryA-2h1rA:
26.2		 3gryA-2h1rA:
38.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 11 GLY A  29
GLY A  31
ASP A  50
ASN A  92
PRO A  94
 None
 0.90A 4dcmA-2h1rA:
10.7		 4dcmA-2h1rA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A 236
LYS A 237
PRO A 234
 None
 1.02A 4dv1L-2h1rA:
undetectable		 4dv1L-2h1rA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 LEU A 105
ILE A  28
LEU A  39
LEU A  26
LEU A 117
 None
 1.30A 4m11A-2h1rA:
undetectable		 4m11A-2h1rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 LEU A 173
LEU A 101
ALA A  91
ALA A 115
ILE A  28
 None
 0.83A 4o2bD-2h1rA:
undetectable		 4o2bD-2h1rA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASN A  34
GLU A  27
GLY A  29
ILE A  49
ILE A  51
 None
 0.77A 4xucA-2h1rA:
12.8		 4xucA-2h1rA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 4 VAL A 131
ALA A 129
ILE A 141
THR A 140
 None
 1.15A 5e4dB-2h1rA:
undetectable		 5e4dB-2h1rA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 CYH A 194
LEU A 264
HIS A 203
LEU A 202
 None
 1.02A 5hpuC-2h1rA:
undetectable
5hpuD-2h1rA:
undetectable		 5hpuC-2h1rA:
7.94
5hpuD-2h1rA:
10.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		6 / 12 GLU A  27
ILE A  28
GLY A  29
GLY A  31
ILE A  51
ASP A  52
 None
 0.90A 6iftA-2h1rA:
24.3		 6iftA-2h1rA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 LEU A   4
GLU A  27
ILE A  28
GLY A  29
GLY A  31
 None
 0.62A 6iftA-2h1rA:
24.3		 6iftA-2h1rA:
31.01