SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT6_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	2h28	HYPOTHETICAL PROTEIN YEEU (Escherichia coli)	5 / 11	LEU A 112 ALA A 65 MET A 70 TYR A 43 LEU A 41	None	1.42A	1kt6A-2h28A: undetectable	1kt6A-2h28A: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT7_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	2h28	HYPOTHETICAL PROTEIN YEEU (Escherichia coli)	5 / 11	LEU A 112 ALA A 65 MET A 70 TYR A 43 LEU A 41	None	1.41A	1kt7A-2h28A: undetectable	1kt7A-2h28A: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT7_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	2h28	HYPOTHETICAL PROTEIN YEEU (Escherichia coli)	5 / 11	LEU A 112 ALA A 65 VAL A 110 MET A 70 LEU A 41	None	1.31A	1kt7A-2h28A: undetectable	1kt7A-2h28A: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FXD_A_DR7A102_1 (POL PROTEIN)	2h28	HYPOTHETICAL PROTEIN YEEU (Escherichia coli)	5 / 11	LEU A 69 ALA A 101 ASP A 102 GLY A 21 PHE A 66	None None MG A5001 (-3.4A) None None	1.01A	2fxdA-2h28A: undetectable	2fxdA-2h28A: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WQ5_A_MIYA1120_1 (PHOSPHOLIPASE A2, ACIDIC)	2h28	HYPOTHETICAL PROTEIN YEEU (Escherichia coli)	4 / 7	LEU A 62 ALA A 32 GLY A 49 ARG A 17	None	0.96A	2wq5A-2h28A: undetectable	2wq5A-2h28A: 20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_B_SVRB516_1 (RNA-DEPENDENT RNA POLYMERASE)	2h28	HYPOTHETICAL PROTEIN YEEU (Escherichia coli)	4 / 7	GLY A 49 ALA A 48 TRP A 20 ARG A 47	None	0.70A	3ur0B-2h28A: undetectable	3ur0B-2h28A: 14.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KT6_A_RTLA184_0","PLASMA RETINOL-BINDING PROTEIN","2h28","HYPOTHETICAL PROTEIN YEEU","Escherichia coli",5,"LEU A 112;ALA A  65;MET A  70;TYR A  43;LEU A  41","None","1.42A","1kt6A-2h28A:undetectable","1kt6A-2h28A:20.22"],["1KT7_A_RTLA184_0","PLASMA RETINOL-BINDING PROTEIN","2h28","HYPOTHETICAL PROTEIN YEEU","Escherichia coli",5,"LEU A 112;ALA A  65;MET A  70;TYR A  43;LEU A  41","None","1.41A","1kt7A-2h28A:undetectable","1kt7A-2h28A:20.22"],["1KT7_A_RTLA184_0","PLASMA RETINOL-BINDING PROTEIN","2h28","HYPOTHETICAL PROTEIN YEEU","Escherichia coli",5,"LEU A 112;ALA A  65;VAL A 110;MET A  70;LEU A  41","None","1.31A","1kt7A-2h28A:undetectable","1kt7A-2h28A:20.22"],["2FXD_A_DR7A102_1","POL PROTEIN","2h28","HYPOTHETICAL PROTEIN YEEU","Escherichia coli",5,"LEU A  69;ALA A 101;ASP A 102;GLY A  21;PHE A  66","None;None; MG A5001 (-3.4A);None;None","1.01A","2fxdA-2h28A:undetectable","2fxdA-2h28A:23.44"],["2WQ5_A_MIYA1120_1","PHOSPHOLIPASE A2, ACIDIC","2h28","HYPOTHETICAL PROTEIN YEEU","Escherichia coli",4,"LEU A  62;ALA A  32;GLY A  49;ARG A  17","None","0.96A","2wq5A-2h28A:undetectable","2wq5A-2h28A:20.14"],["3UR0_B_SVRB516_1","RNA-DEPENDENT RNA POLYMERASE","2h28","HYPOTHETICAL PROTEIN YEEU","Escherichia coli",4,"GLY A  49;ALA A  48;TRP A  20;ARG A  47","None","0.70A","3ur0B-2h28A:undetectable","3ur0B-2h28A:14.76"]]