SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A  16
ASN A  17
LEU A  19
ARG A  49
LEU A  72
 None
 1.22A 1zucB-2h2mA:
undetectable		 1zucB-2h2mA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A  12
PRO A  11
LEU A  15
 None
 0.61A 2po5B-2h2mA:
undetectable		 2po5B-2h2mA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A  12
PRO A  11
LEU A  15
 None
 0.56A 2po7B-2h2mA:
undetectable		 2po7B-2h2mA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A  16
ASN A  17
LEU A  19
ARG A  49
LEU A  72
 None
 1.23A 2w8yB-2h2mA:
undetectable		 2w8yB-2h2mA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A  16
ASN A  17
LEU A  19
ARG A  49
LEU A  72
 None
 1.22A 3d90A-2h2mA:
undetectable		 3d90A-2h2mA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		6 / 11 LEU A  39
LEU A  35
ALA A  18
LEU A  15
MET A  55
VAL A  43
 None
 1.37A 3e22B-2h2mA:
undetectable		 3e22B-2h2mA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		6 / 11 LEU A  39
LEU A  35
ALA A  18
LEU A  15
MET A  55
VAL A  43
 None
 1.38A 3e22D-2h2mA:
undetectable		 3e22D-2h2mA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A  12
PRO A  11
LEU A  15
 None
 0.51A 3hcrA-2h2mA:
undetectable		 3hcrA-2h2mA:
15.91