SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2h2y UBIQUITIN-CONJUGATIN
G ENZYME
(Plasmodium
falciparum) 		5 / 10 ILE A  71
PHE A  88
ILE A 127
SER A 128
HIS A  95
 None
 0.96A 3o1cA-2h2yA:
undetectable		 3o1cA-2h2yA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 2h2y UBIQUITIN-CONJUGATIN
G ENZYME
(Plasmodium
falciparum) 		5 / 12 GLY A 102
VAL A  98
ILE A 104
TYR A  69
LEU A 130
 None
 1.05A 4pd4C-2h2yA:
undetectable		 4pd4C-2h2yA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 2h2y UBIQUITIN-CONJUGATIN
G ENZYME
(Plasmodium
falciparum) 		5 / 12 SER A 120
ASN A  31
GLU A  28
VAL A 108
TYR A 113
 None
 1.49A 5iqdC-2h2yA:
0.8		 5iqdC-2h2yA:
21.26