SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		5 / 12 PHE X  30
LEU X  87
TYR X  77
TYR X  85
LEU X  22
 None
 1.45A 1p33A-2h36X:
undetectable		 1p33A-2h36X:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		5 / 12 PHE X  30
LEU X  87
TYR X  77
TYR X  85
LEU X  22
 None
 1.47A 1p33B-2h36X:
undetectable		 1p33B-2h36X:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		5 / 12 PHE X  30
LEU X  87
TYR X  77
TYR X  85
LEU X  22
 None
 1.48A 1p33C-2h36X:
undetectable		 1p33C-2h36X:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		4 / 7 TYR X  85
ALA X  25
LEU X  22
PHE X  89
 None
 1.09A 2vcvA-2h36X:
undetectable		 2vcvA-2h36X:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		4 / 8 PHE X  30
TYR X  85
VAL X 103
LEU X  22
 None
 1.02A 3jq7C-2h36X:
undetectable		 3jq7C-2h36X:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		3 / 3 ASN X  58
ASP X  60
ASP X  80
 None
 0.76A 4obwD-2h36X:
undetectable		 4obwD-2h36X:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		5 / 12 ILE X 100
LEU X  55
SER X  62
GLU X  88
PHE X  89
 None
 1.22A 5il1A-2h36X:
undetectable		 5il1A-2h36X:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 2h36 HYPOTHETICAL PROTEIN
SIFV0014
(Sulfolobus
islandicus
filamentous
virus) 		4 / 6 GLU X 102
LYS X  40
PHE X  41
PRO X  44
 None
 1.40A 6fgdA-2h36X:
2.6		 6fgdA-2h36X:
14.24