SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  27
LEU A  32
ALA A  36
VAL A  52
LEU A  66
 None
 1.04A 1s9pA-2h3jA:
undetectable		 1s9pA-2h3jA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  27
LEU A  32
ALA A  36
VAL A  52
LEU A  66
 None
 1.08A 1s9pD-2h3jA:
undetectable		 1s9pD-2h3jA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  68
SER A  16
TYR A  15
LEU A  27
 None
 1.02A 1xz1A-2h3jA:
undetectable		 1xz1A-2h3jA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  68
SER A  16
TYR A  15
LEU A  27
 None
 1.02A 1xz3A-2h3jA:
undetectable		 1xz3A-2h3jA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  68
SER A  16
TYR A  15
LEU A  27
 None
 1.02A 3f33A-2h3jA:
undetectable		 3f33A-2h3jA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  68
SER A  16
TYR A  15
LEU A  27
 None
 1.02A 3ravA-2h3jA:
undetectable		 3ravA-2h3jA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  68
SER A  16
TYR A  15
LEU A  27
 None
 1.01A 3rd0A-2h3jA:
undetectable		 3rd0A-2h3jA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  38
THR A  54
VAL A  52
LEU A  66
ILE A  50
 None
 1.12A 3tbgD-2h3jA:
undetectable		 3tbgD-2h3jA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 2h3j HYPOTHETICAL PROTEIN
PA4359
(Pseudomonas
aeruginosa) 		4 / 7 PRO A  73
ARG A  11
GLY A  35
PRO A  34
 None
 1.36A 3ucbB-2h3jA:
undetectable		 3ucbB-2h3jA:
18.37