SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2h3l LAP2 PROTEIN
(Homo
sapiens) 		4 / 8 LEU A1394
SER A1393
LEU A1404
PHE A1398
 None
 0.81A 3ln1A-2h3lA:
undetectable		 3ln1A-2h3lA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2h3l LAP2 PROTEIN
(Homo
sapiens) 		4 / 7 LEU A1394
SER A1393
LEU A1404
PHE A1398
 None
 0.81A 3ln1B-2h3lA:
undetectable		 3ln1B-2h3lA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 2h3l LAP2 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A1369
LEU A1332
LEU A1404
ASN A1379
ILE A1336
 None
 1.00A 5itzB-2h3lA:
undetectable		 5itzB-2h3lA:
14.75