SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h4t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 ASP A 232
ARG A 225
ILE A 127
 None
 0.83A 1a4gB-2h4tA:
undetectable		 1a4gB-2h4tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 THR A  60
GLU A  88
THR A  89
LEU A 573
 None
 1.15A 1d4fC-2h4tA:
undetectable		 1d4fC-2h4tA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 LEU A  95
LEU A 573
ALA A  67
MET A  61
LEU A  57
 None
 1.29A 1iiuA-2h4tA:
undetectable		 1iiuA-2h4tA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 0.91A 1iwiA-2h4tA:
undetectable		 1iwiA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 ALA A 650
VAL A 466
LEU A 469
ALA A 470
ALA A 474
 None
 1.02A 1jinA-2h4tA:
undetectable		 1jinA-2h4tA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 LEU A  95
LEU A 573
ALA A  67
MET A  61
LEU A  57
 None
 1.25A 1kt5A-2h4tA:
undetectable		 1kt5A-2h4tA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 LEU A  95
LEU A 573
ALA A  67
MET A  61
LEU A  57
 None
 1.28A 1kt6A-2h4tA:
undetectable		 1kt6A-2h4tA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 LEU A  95
LEU A 573
ALA A  67
MET A  61
LEU A  57
 None
 1.29A 1kt7A-2h4tA:
undetectable		 1kt7A-2h4tA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 4 ILE A 647
LEU A 644
VAL A 640
ALA A 633
 None
 0.94A 1mz9A-2h4tA:
undetectable		 1mz9A-2h4tA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 ILE A 647
LEU A 644
VAL A 640
ALA A 633
 None
 0.97A 1mz9C-2h4tA:
undetectable		 1mz9C-2h4tA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.03A 1t85A-2h4tA:
undetectable		 1t85A-2h4tA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 0.96A 1t87A-2h4tA:
undetectable		 1t87A-2h4tA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 LEU A 441
PHE A 610
GLY A 611
VAL A 625
ALA A 633
 None
 1.03A 1v2xA-2h4tA:
undetectable		 1v2xA-2h4tA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ALA A 367
MET A 342
LEU A 599
ILE A 443
HIS A 337
 None
None
D12  A1703 (-4.2A)
None
None
 1.06A 1xzxX-2h4tA:
undetectable		 1xzxX-2h4tA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 10 ALA A 430
LEU A 419
LEU A 306
SER A 293
LEU A 291
 None
 1.33A 2ceoB-2h4tA:
undetectable		 2ceoB-2h4tA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.01A 2feuB-2h4tA:
undetectable		 2feuB-2h4tA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ILE A 612
ALA A 505
TYR A 614
PHE A 471
SER A 513
 None
 1.35A 2gl0A-2h4tA:
undetectable
2gl0C-2h4tA:
0.6		 2gl0A-2h4tA:
15.97
2gl0C-2h4tA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ALA A 367
MET A 342
LEU A 599
ILE A 443
HIS A 337
 None
None
D12  A1703 (-4.2A)
None
None
 1.06A 2h77A-2h4tA:
undetectable		 2h77A-2h4tA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 TYR A 561
ASP A 118
TYR A 557
HIS A 372
 None
 1.40A 2ha2A-2h4tA:
undetectable		 2ha2A-2h4tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 TYR A 561
ASP A 118
TYR A 557
HIS A 372
 None
 1.32A 2ha2B-2h4tA:
undetectable		 2ha2B-2h4tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 6 ARG A  63
GLY A 551
PRO A  53
THR A 491
 None
 1.01A 2m2oB-2h4tA:
undetectable		 2m2oB-2h4tA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 6 PHE A 356
LEU A 243
ALA A 159
LEU A 163
 None
 0.97A 2vcvB-2h4tA:
undetectable		 2vcvB-2h4tA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 356
LEU A 243
ALA A 159
LEU A 163
 None
 0.99A 2vcvG-2h4tA:
2.5		 2vcvG-2h4tA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 LEU A 220
TYR A 217
GLN A 216
 None
 0.74A 2wekA-2h4tA:
undetectable		 2wekA-2h4tA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 8 LEU A 327
ILE A 276
LEU A 273
THR A 156
LEU A 325
 None
 0.95A 2xfhA-2h4tA:
undetectable		 2xfhA-2h4tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 6 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.00A 2zuiA-2h4tA:
undetectable		 2zuiA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.02A 2zwuA-2h4tA:
undetectable		 2zwuA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.04A 3fwfA-2h4tA:
undetectable		 3fwfA-2h4tA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.02A 3fwfB-2h4tA:
undetectable		 3fwfB-2h4tA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.02A 3fwjA-2h4tA:
undetectable		 3fwjA-2h4tA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ALA A 367
MET A 342
LEU A 599
ILE A 443
HIS A 337
 None
None
D12  A1703 (-4.2A)
None
None
 1.06A 3gwsX-2h4tA:
undetectable		 3gwsX-2h4tA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 LEU A 325
LEU A 358
ARG A 350
ALA A 367
ASP A 328
 None
 0.88A 3gwwA-2h4tA:
undetectable		 3gwwA-2h4tA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 GLY A 452
VAL A 616
LEU A 461
MET A 532
LEU A 469
 None
 1.37A 3h52D-2h4tA:
undetectable		 3h52D-2h4tA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 ARG A 450
ASP A 649
ASP A 646
PHE A 448
 None
 1.36A 3kivA-2h4tA:
undetectable		 3kivA-2h4tA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 GLU A 572
LEU A 575
ASP A 576
 None
 0.46A 3ko0A-2h4tA:
undetectable		 3ko0A-2h4tA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 LEU A 587
PHE A 134
PHE A 471
ALA A 470
ILE A 621
 None
 1.07A 3nxuA-2h4tA:
undetectable		 3nxuA-2h4tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 LEU A 587
PHE A 134
PHE A 471
ALA A 470
ILE A 621
 None
 1.08A 3nxuB-2h4tA:
undetectable		 3nxuB-2h4tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 LEU A  83
ARG A  79
PRO A 577
ALA A 578
 None
 1.40A 3vm4A-2h4tA:
undetectable		 3vm4A-2h4tA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.03A 3wrhA-2h4tA:
undetectable		 3wrhA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.03A 3wrjA-2h4tA:
undetectable		 3wrjA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.02A 3wrlE-2h4tA:
undetectable		 3wrlE-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.05A 3wrmA-2h4tA:
undetectable		 3wrmA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.02A 3wrmF-2h4tA:
undetectable		 3wrmF-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 PRO A  70
LEU A  71
LEU A 587
PHE A 636
TYR A 614
 None
 1.41A 4a79B-2h4tA:
undetectable		 4a79B-2h4tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 TRP A 299
TRP A 351
THR A 224
 None
 1.35A 4bboB-2h4tA:
undetectable		 4bboB-2h4tA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 SER A 293
HIS A 344
TYR A 290
VAL A 438
 None
 1.22A 4eohB-2h4tA:
undetectable		 4eohB-2h4tA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 0.96A 4l4aA-2h4tA:
undetectable		 4l4aA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 PHE A 221
THR A 165
LEU A  35
VAL A 387
 None
 1.05A 4l4gA-2h4tA:
undetectable		 4l4gA-2h4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 9 THR A 156
LEU A 358
ALA A 159
LEU A 220
PHE A 383
 None
 1.41A 4ltwA-2h4tA:
2.2		 4ltwA-2h4tA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 LEU A 556
LEU A 559
LEU A 562
ALA A 563
MET A  61
 None
 0.76A 4ltwA-2h4tA:
2.2		 4ltwA-2h4tA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 ASP A 232
ASN A 230
SER A 126
 None
 0.80A 4obwA-2h4tA:
undetectable		 4obwA-2h4tA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 6 ALA A 379
ASP A 213
LEU A 220
SER A 223
 None
 1.01A 4ot2A-2h4tA:
undetectable		 4ot2A-2h4tA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 LEU A 644
GLU A 645
PHE A 516
ALA A 650
PHE A 448
 None
 1.13A 4wnuA-2h4tA:
undetectable		 4wnuA-2h4tA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 VAL A 360
VAL A 387
SER A 391
VAL A 157
LEU A 358
 None
 1.11A 5iktA-2h4tA:
undetectable		 5iktA-2h4tA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 ASN A 632
TYR A 479
CYH A 639
 None
 0.92A 5lsuB-2h4tA:
undetectable		 5lsuB-2h4tA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 8 LEU A 199
VAL A 195
HIS A  44
LEU A 206
ILE A 192
 None
 1.47A 5v0vA-2h4tA:
2.1		 5v0vA-2h4tA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 MET A  43
ASP A 213
ARG A 219
 None
 1.21A 5z6jA-2h4tA:
undetectable		 5z6jA-2h4tA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 THR A 491
THR A 543
GLU A 487
SER A 488
 None
 1.14A 6c06C-2h4tA:
undetectable		 6c06C-2h4tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 ARG A  79
LEU A  83
PHE A  87
 None
 0.66A 6nknP-2h4tA:
undetectable		 6nknP-2h4tA:
17.07