SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h56'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2h56 DNA-3-METHYLADENINE
GLYCOSIDASE
(Bacillus
halodurans) 		5 / 12 LEU A 195
LEU A 179
LEU A 160
MET A 141
PHE A 145
 None
 1.37A 1d4fD-2h56A:
undetectable		 1d4fD-2h56A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 2h56 DNA-3-METHYLADENINE
GLYCOSIDASE
(Bacillus
halodurans) 		4 / 7 PHE A 145
LEU A 195
THR A  35
LYS A   0
 None
 1.15A 1rmtB-2h56A:
undetectable		 1rmtB-2h56A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 2h56 DNA-3-METHYLADENINE
GLYCOSIDASE
(Bacillus
halodurans) 		5 / 12 VAL A  44
VAL A  68
LEU A  67
LEU A  78
GLY A  62
 None
 1.31A 3pghA-2h56A:
undetectable		 3pghA-2h56A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2h56 DNA-3-METHYLADENINE
GLYCOSIDASE
(Bacillus
halodurans) 		4 / 6 CYH A 194
LEU A 153
HIS A 182
LEU A 179
 None
 0.87A 5hpuC-2h56A:
undetectable
5hpuD-2h56A:
undetectable		 5hpuC-2h56A:
6.09
5hpuD-2h56A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2h56 DNA-3-METHYLADENINE
GLYCOSIDASE
(Bacillus
halodurans) 		4 / 6 CYH A 194
LEU A 153
HIS A 182
LEU A 179
 None
 1.06A 5hpuC-2h56A:
undetectable
5hpuD-2h56A:
undetectable		 5hpuC-2h56A:
6.09
5hpuD-2h56A:
9.57