SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h5n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 2h5n HYPOTHETICAL PROTEIN
PG_1108
(Porphyromonas
gingivalis) 		5 / 11 ARG A  83
LEU A  91
ILE A  76
ALA A  20
THR A  19
 None
 1.34A 2v0mD-2h5nA:
undetectable		 2v0mD-2h5nA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 2h5n HYPOTHETICAL PROTEIN
PG_1108
(Porphyromonas
gingivalis) 		5 / 12 GLU A  39
VAL A 123
ILE A 101
ILE A  94
GLU A  46
 None
 1.35A 4a99A-2h5nA:
undetectable
4a99C-2h5nA:
undetectable		 4a99A-2h5nA:
14.54
4a99C-2h5nA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 2h5n HYPOTHETICAL PROTEIN
PG_1108
(Porphyromonas
gingivalis) 		4 / 6 ARG A  83
GLU A  81
MET A  79
ASP A  80
 None
 1.10A 4cevE-2h5nA:
undetectable
4cevF-2h5nA:
undetectable		 4cevE-2h5nA:
19.80
4cevF-2h5nA:
19.80