SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		3 / 3 TRP A  92
VAL A 135
TRP A 133
 None
 1.05A 1c4dC-2h6eA:
undetectable
1c4dD-2h6eA:
undetectable		 1c4dC-2h6eA:
5.63
1c4dD-2h6eA:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		3 / 3 TRP A 133
VAL A  87
TRP A  92
 None
 1.15A 1c4dC-2h6eA:
undetectable
1c4dD-2h6eA:
undetectable		 1c4dC-2h6eA:
5.63
1c4dD-2h6eA:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.90A 1c6zA-2h6eA:
undetectable		 1c6zA-2h6eA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.97A 1c6zB-2h6eA:
undetectable		 1c6zB-2h6eA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
GLY A 115
ILE A  33
ILE A  35
 None
 0.93A 1hshC-2h6eA:
undetectable		 1hshC-2h6eA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.89A 1sduB-2h6eA:
undetectable		 1sduB-2h6eA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 8 LEU A 255
ALA A 226
ILE A 230
GLY A 201
 None
 0.83A 1sv9A-2h6eA:
undetectable		 1sv9A-2h6eA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 269
VAL A 176
ILE A 179
GLY A 180
GLY A 181
 None
 0.89A 2avsA-2h6eA:
undetectable		 2avsA-2h6eA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.90A 2avsB-2h6eA:
undetectable		 2avsB-2h6eA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 11 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.91A 2fxeB-2h6eA:
undetectable		 2fxeB-2h6eA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 1.01A 2hs1A-2h6eA:
undetectable		 2hs1A-2h6eA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.94A 2nmyB-2h6eA:
undetectable		 2nmyB-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.92A 2o4sA-2h6eA:
undetectable		 2o4sA-2h6eA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.90A 2pymB-2h6eA:
undetectable		 2pymB-2h6eA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.91A 2pynB-2h6eA:
undetectable		 2pynB-2h6eA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.91A 2q63B-2h6eA:
undetectable		 2q63B-2h6eA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.95A 2q64A-2h6eA:
undetectable		 2q64A-2h6eA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.92A 2qakB-2h6eA:
undetectable		 2qakB-2h6eA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 VAL A 268
ILE A 179
ILE A 199
LEU A 190
ILE A 243
 None
 1.05A 3clbC-2h6eA:
2.9		 3clbC-2h6eA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.94A 3cyxA-2h6eA:
undetectable		 3cyxA-2h6eA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.92A 3d1xB-2h6eA:
undetectable		 3d1xB-2h6eA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 11 VAL A 268
ILE A 179
ILE A 199
LEU A 190
ILE A 243
 None
 1.04A 3hbbC-2h6eA:
2.4		 3hbbC-2h6eA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.94A 3jvyB-2h6eA:
undetectable		 3jvyB-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.92A 3nduB-2h6eA:
undetectable		 3nduB-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 1.00A 3ndxA-2h6eA:
undetectable		 3ndxA-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.93A 3oxcA-2h6eA:
undetectable		 3oxcA-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 1.03A 3oxcB-2h6eA:
undetectable		 3oxcB-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.97A 3oxxA-2h6eA:
undetectable		 3oxxA-2h6eA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.96A 3oxxC-2h6eA:
undetectable		 3oxxC-2h6eA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.95A 3pwrA-2h6eA:
undetectable		 3pwrA-2h6eA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.91A 3pwrB-2h6eA:
undetectable		 3pwrB-2h6eA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 7 ILE A 189
VAL A 303
LEU A 306
SER A 307
 None
 0.67A 3r9vA-2h6eA:
undetectable
3r9vB-2h6eA:
undetectable		 3r9vA-2h6eA:
21.14
3r9vB-2h6eA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 5 ASP A 244
SER A 276
VAL A 275
GLY A 247
 None
 0.95A 3rxhA-2h6eA:
undetectable		 3rxhA-2h6eA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
GLY A 115
ILE A  33
ILE A  35
 None
 0.90A 3s54A-2h6eA:
undetectable		 3s54A-2h6eA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.93A 3tkgA-2h6eA:
undetectable		 3tkgA-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.96A 3tkgB-2h6eA:
undetectable		 3tkgB-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.97A 3tkgC-2h6eA:
undetectable		 3tkgC-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 290
ILE A 107
GLY A 157
ILE A 266
ILE A 159
 None
 1.02A 3uj6A-2h6eA:
5.3		 3uj6A-2h6eA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 8 GLY A 121
GLY A 120
SER A 123
ILE A  23
LEU A  32
 None
 1.30A 3v1nA-2h6eA:
undetectable		 3v1nA-2h6eA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.93A 4jecB-2h6eA:
undetectable		 4jecB-2h6eA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 5 VAL A 128
LEU A 134
ILE A  33
LEU A  32
 None
 0.87A 4mghA-2h6eA:
2.2		 4mghA-2h6eA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 190
VAL A 176
GLY A 247
THR A 186
THR A 251
 None
 1.39A 4mubA-2h6eA:
undetectable		 4mubA-2h6eA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		6 / 12 GLY A  64
GLY A 120
ASN A  67
ALA A   7
LEU A   8
GLY A  37
 None
 1.30A 4n09C-2h6eA:
3.7		 4n09C-2h6eA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 5 ASN A  67
PRO A 114
GLY A 120
ASP A  44
 None
 1.03A 4n48B-2h6eA:
6.6		 4n48B-2h6eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 5 ASN A  67
PRO A 114
GLY A 121
ASP A  44
 None
 0.99A 4n48B-2h6eA:
6.6		 4n48B-2h6eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
ILE A  62
GLY A 115
ILE A  35
 None
 0.94A 4njvD-2h6eA:
undetectable		 4njvD-2h6eA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 TYR A 315
GLY A 180
GLY A 181
ILE A 187
GLY A 201
 None
 0.99A 4obwB-2h6eA:
7.0		 4obwB-2h6eA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		3 / 3 THR A 117
ASN A 106
PHE A 105
 None
 0.84A 4pd9A-2h6eA:
undetectable		 4pd9A-2h6eA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 6 ALA A 158
ILE A 312
GLY A 152
ILE A 243
 None
 0.59A 4r21A-2h6eA:
undetectable		 4r21A-2h6eA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 9 ALA A 158
ILE A 312
GLY A 152
ILE A 243
VAL A 184
 None
 1.01A 4r21B-2h6eA:
undetectable		 4r21B-2h6eA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 8 LEU A 127
VAL A  88
LEU A 134
ILE A  33
 None
 0.82A 4r38D-2h6eA:
undetectable		 4r38D-2h6eA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 THR A 154
SER A 155
GLY A 291
GLY A 247
LEU A 245
 None
 1.30A 4uinH-2h6eA:
undetectable
4uinL-2h6eA:
undetectable		 4uinH-2h6eA:
20.35
4uinL-2h6eA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 8 ALA A 212
ALA A 217
ILE A 187
ALA A 242
LEU A 190
 None
 1.36A 4v1fA-2h6eA:
undetectable
4v1fB-2h6eA:
undetectable		 4v1fA-2h6eA:
13.53
4v1fB-2h6eA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 258
ALA A 226
ASN A 177
VAL A 173
ALA A 239
 None
 1.18A 4x1iB-2h6eA:
3.6		 4x1iB-2h6eA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 ALA A 226
ASN A 177
VAL A 173
ALA A 239
ILE A 199
 None
 0.98A 4x20B-2h6eA:
3.8		 4x20B-2h6eA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  39
ALA A  38
GLY A 115
ILE A  33
ILE A  35
 None
 0.90A 5e5kB-2h6eA:
undetectable		 5e5kB-2h6eA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 12 SER A 276
VAL A 246
GLY A 269
ASN A 177
GLU A 222
 None
 1.13A 6bqgA-2h6eA:
undetectable		 6bqgA-2h6eA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		4 / 8 LEU A 137
LEU A 140
GLY A  39
ARG A 339
 None
 0.82A 6ce2A-2h6eA:
undetectable		 6ce2A-2h6eA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2h6e D-ARABINOSE
1-DEHYDROGENASE
(Sulfolobus
solfataricus) 		5 / 8 GLY A 180
VAL A 246
GLY A 152
SER A 155
ALA A 158
 None
 1.43A 6hu9H-2h6eA:
undetectable
6hu9e-2h6eA:
undetectable		 6hu9H-2h6eA:
13.49
6hu9e-2h6eA:
16.57