SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		4 / 8 SER C 631
ALA C 633
TRP C 632
PHE C 686
 None
 1.06A 1dmiA-2h7vC:
undetectable
1dmiB-2h7vC:
undetectable		 1dmiA-2h7vC:
20.89
1dmiB-2h7vC:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		5 / 10 ALA C 565
LEU C 477
ASP C 481
ASN C 498
ILE C 501
 None
 1.09A 3wdmD-2h7vC:
undetectable		 3wdmD-2h7vC:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		4 / 5 ARG C 545
VAL C 539
LEU C 470
SER C 471
 None
 1.31A 4e1gA-2h7vC:
undetectable		 4e1gA-2h7vC:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		5 / 10 GLN C 552
ASP C 558
ARG C 545
ASP C 481
GLU C 484
 None
 1.49A 4fevA-2h7vC:
undetectable		 4fevA-2h7vC:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 MET C 664
GLN C 663
ARG C 662
 None
 1.02A 5ewzB-2h7vC:
4.5		 5ewzB-2h7vC:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 LEU C 693
LEU C 714
ARG C 684
 None
 0.49A 5hnzB-2h7vC:
undetectable		 5hnzB-2h7vC:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 MET C 664
GLN C 663
ARG C 662
 None
 1.09A 5m35B-2h7vC:
6.4		 5m35B-2h7vC:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 MET C 664
GLN C 663
ARG C 662
 None
 1.10A 5m36A-2h7vC:
4.8		 5m36A-2h7vC:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		4 / 6 LEU C 550
GLN C 607
LEU C 608
LEU C 562
 None
 1.13A 5yvnA-2h7vC:
3.6		 5yvnA-2h7vC:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		4 / 6 LEU C 464
ALA C 459
LEU C 470
THR C 571
 None
 0.87A 6f88B-2h7vC:
undetectable		 6f88B-2h7vC:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 MET C 664
GLN C 663
ARG C 662
 None
 1.12A 6fn9A-2h7vC:
6.5		 6fn9A-2h7vC:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 MET C 664
GLN C 663
ARG C 662
 None
 1.14A 6fnaB-2h7vC:
6.5		 6fnaB-2h7vC:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2h7v PROTEIN KINASE YPKA
(Yersinia
pseudotuberculos
is) 		3 / 3 MET C 664
GLN C 663
ARG C 662
 None
 1.11A 6fnbA-2h7vC:
6.3		 6fnbA-2h7vC:
23.03