SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2h7w CHAGASIN
(Trypanosoma
cruzi) 		3 / 3 LYS A   7
TYR A  89
PRO A  27
 None
 1.30A 2j9cC-2h7wA:
undetectable		 2j9cC-2h7wA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2h7w CHAGASIN
(Trypanosoma
cruzi) 		3 / 3 TYR A  37
GLU A  71
THR A  32
 None
 0.89A 2y7hB-2h7wA:
2.8		 2y7hB-2h7wA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2h7w CHAGASIN
(Trypanosoma
cruzi) 		4 / 7 VAL A  75
ILE A  24
PHE A 103
VAL A  85
 None
 0.78A 5bmvC-2h7wA:
undetectable		 5bmvC-2h7wA:
15.93