SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 7 LEU A 267
ASP A 263
LEU A 260
ILE A 214
 None
 1.07A 1n13I-2h8oA:
undetectable
1n13L-2h8oA:
undetectable		 1n13I-2h8oA:
10.75
1n13L-2h8oA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 7 LEU A 108
ILE A  94
ALA A 112
PRO A  90
 None
 0.89A 1oniB-2h8oA:
undetectable
1oniC-2h8oA:
undetectable		 1oniB-2h8oA:
19.69
1oniC-2h8oA:
19.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 SER A 121
LEU A 122
ARG A 136
GLN A 198
THR A 222
 None
 1.00A 1rqjA-2h8oA:
35.7		 1rqjA-2h8oA:
40.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 SER A 121
LEU A 122
ASP A 131
ARG A 136
THR A 222
 None
 0.92A 1rqjA-2h8oA:
35.7		 1rqjA-2h8oA:
40.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 SER A 121
LEU A 122
ARG A 136
GLN A 198
THR A 222
 None
 0.98A 1rqjB-2h8oA:
35.6		 1rqjB-2h8oA:
40.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 SER A 121
LEU A 122
ASP A 131
ARG A 136
THR A 222
 None
 0.90A 1rqjB-2h8oA:
35.6		 1rqjB-2h8oA:
40.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 12 ALA A 261
ASP A 262
ASP A 263
GLY A 255
ILE A 254
 None
 0.99A 1sguB-2h8oA:
undetectable		 1sguB-2h8oA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		3 / 3 ARG A 227
ARG A 248
ILE A 235
 None
 0.64A 1uobA-2h8oA:
undetectable		 1uobA-2h8oA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 125
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.44A 1yv5A-2h8oA:
24.5		 1yv5A-2h8oA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ASP A 125
ARG A 136
GLN A 198
THR A 222
 None
 1.15A 1yv5A-2h8oA:
24.5		 1yv5A-2h8oA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 5 LEU A 161
LEU A 158
LEU A  73
LEU A  74
 None
 0.90A 2ab2B-2h8oA:
undetectable		 2ab2B-2h8oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 125
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.48A 2f8zF-2h8oA:
25.5		 2f8zF-2h8oA:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ASP A 125
ARG A 136
GLN A 198
THR A 222
 None
 1.17A 2f8zF-2h8oA:
25.5		 2f8zF-2h8oA:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.43A 2q58A-2h8oA:
11.8		 2q58A-2h8oA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 4 LYS A 319
LEU A  99
ALA A 321
LEU A 323
 None
 1.33A 2roxA-2h8oA:
undetectable		 2roxA-2h8oA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 GLU A 105
ILE A 236
GLY A 102
LEU A 323
ILE A  94
 None
 1.26A 3adsA-2h8oA:
undetectable		 3adsA-2h8oA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 THR A 216
ALA A 224
GLY A 223
THR A 222
ASP A 201
 None
 1.35A 3mg0H-2h8oA:
undetectable
3mg0I-2h8oA:
undetectable		 3mg0H-2h8oA:
21.19
3mg0I-2h8oA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 8 ALA A 261
ASP A 262
ASP A 263
GLY A 255
ILE A 254
 None
 1.15A 3so9A-2h8oA:
undetectable		 3so9A-2h8oA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 233
GLY A 238
SER A 239
LEU A  92
GLY A 251
 None
 1.22A 4blvB-2h8oA:
undetectable		 4blvB-2h8oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 9 ALA A 261
ASP A 262
ASP A 263
GLY A 255
ILE A 254
 None
 1.03A 4dqcB-2h8oA:
undetectable		 4dqcB-2h8oA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 125
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.46A 4nkeA-2h8oA:
24.5		 4nkeA-2h8oA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ASP A 125
ARG A 136
GLN A 198
THR A 222
 None
 1.17A 4nkeA-2h8oA:
24.5		 4nkeA-2h8oA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 ARG A  89
LEU A  92
SER A  96
LEU A  88
LEU A 323
 None
 1.26A 4or0A-2h8oA:
3.1		 4or0A-2h8oA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 ARG A  89
LEU A  92
SER A  96
LEU A  88
LEU A 323
 None
 1.29A 4or0B-2h8oA:
3.1		 4or0B-2h8oA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 125
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.48A 4rxdA-2h8oA:
24.1		 4rxdA-2h8oA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ASP A 125
ARG A 136
GLN A 198
THR A 222
 None
 1.16A 4rxdA-2h8oA:
24.1		 4rxdA-2h8oA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 125
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.47A 4rxdB-2h8oA:
24.4		 4rxdB-2h8oA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ASP A 125
ARG A 136
GLN A 198
THR A 222
 None
 1.14A 4rxdB-2h8oA:
24.4		 4rxdB-2h8oA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 125
ARG A 136
GLN A 198
LYS A 221
THR A 222
 None
 1.47A 4rxdC-2h8oA:
23.9		 4rxdC-2h8oA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 122
ASP A 125
ARG A 136
GLN A 198
THR A 222
 None
 1.15A 4rxdC-2h8oA:
23.9		 4rxdC-2h8oA:
26.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 8 SER A 121
LEU A 122
ASP A 131
ARG A 136
MET A 194
 None
 0.65A 4umjA-2h8oA:
37.0		 4umjA-2h8oA:
41.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 9 SER A 121
LEU A 122
ARG A 136
GLN A 198
THR A 222
 None
 1.02A 4umjB-2h8oA:
37.7		 4umjB-2h8oA:
41.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 9 SER A 121
LEU A 122
ASP A 125
GLN A 198
THR A 222
 None
 1.19A 4umjB-2h8oA:
37.7		 4umjB-2h8oA:
41.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		6 / 9 SER A 121
LEU A 122
ASP A 131
ARG A 136
MET A 194
THR A 222
 None
 0.65A 4umjB-2h8oA:
37.7		 4umjB-2h8oA:
41.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 LEU A 100
LEU A  99
LEU A 247
ALA A 314
LEU A 313
 None
 1.11A 4wg0B-2h8oA:
undetectable
4wg0C-2h8oA:
undetectable
4wg0D-2h8oA:
undetectable		 4wg0B-2h8oA:
3.90
4wg0C-2h8oA:
3.90
4wg0D-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 LEU A 100
LEU A  99
LEU A 247
ALA A 314
LEU A 313
 None
 1.12A 4wg0D-2h8oA:
undetectable
4wg0E-2h8oA:
undetectable
4wg0F-2h8oA:
undetectable		 4wg0D-2h8oA:
3.90
4wg0E-2h8oA:
3.90
4wg0F-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 LEU A 100
LEU A  99
LEU A 247
ALA A 314
LEU A 313
 None
 1.13A 4wg0F-2h8oA:
undetectable
4wg0G-2h8oA:
undetectable
4wg0H-2h8oA:
undetectable		 4wg0F-2h8oA:
3.90
4wg0G-2h8oA:
3.90
4wg0H-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 LEU A 100
LEU A  99
LEU A 247
ALA A 314
LEU A 313
 None
 1.15A 4wg0H-2h8oA:
undetectable
4wg0I-2h8oA:
undetectable
4wg0J-2h8oA:
undetectable		 4wg0H-2h8oA:
3.90
4wg0I-2h8oA:
3.90
4wg0J-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 ALA A 314
LEU A 313
LEU A 247
LEU A 100
LEU A  99
 None
 1.14A 4wg0G-2h8oA:
undetectable
4wg0H-2h8oA:
undetectable
4wg0I-2h8oA:
undetectable		 4wg0G-2h8oA:
3.90
4wg0H-2h8oA:
3.90
4wg0I-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 ALA A 314
LEU A 313
LEU A 247
LEU A 100
LEU A  99
 None
 1.17A 4wg0I-2h8oA:
undetectable
4wg0J-2h8oA:
undetectable
4wg0K-2h8oA:
undetectable		 4wg0I-2h8oA:
3.90
4wg0J-2h8oA:
3.90
4wg0K-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 ALA A 314
LEU A 313
LEU A 247
LEU A 100
LEU A  99
 None
 1.14A 4wg0K-2h8oA:
undetectable
4wg0L-2h8oA:
undetectable
4wg0M-2h8oA:
undetectable		 4wg0K-2h8oA:
3.90
4wg0L-2h8oA:
3.90
4wg0M-2h8oA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 6 HIS A 118
GLY A  85
GLU A 115
ARG A  87
 None
 1.09A 4zbqA-2h8oA:
3.3		 4zbqA-2h8oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 ASN A  38
LEU A  88
LEU A 323
ILE A 322
LEU A  92
 None
 0.87A 4zowA-2h8oA:
1.7		 4zowA-2h8oA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 11 THR A 216
ALA A 224
GLY A 223
THR A 222
ASP A 201
 None
 1.31A 5bxnV-2h8oA:
undetectable
5bxnW-2h8oA:
undetectable		 5bxnV-2h8oA:
20.12
5bxnW-2h8oA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		3 / 3 GLN A 218
THR A 288
ASP A 263
 None
 0.87A 5k9dA-2h8oA:
undetectable		 5k9dA-2h8oA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 10 GLY A 102
GLY A 101
ILE A 236
ALA A  98
GLY A 233
 None
 1.12A 6e5zA-2h8oA:
undetectable		 6e5zA-2h8oA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 225
GLY A 111
ILE A 166
VAL A  93
ILE A 236
 None
 1.06A 6ectA-2h8oA:
undetectable		 6ectA-2h8oA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 4 LYS A 319
LEU A  99
ALA A 321
LEU A 323
 None
 1.20A 6gnrA-2h8oA:
undetectable		 6gnrA-2h8oA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		4 / 4 LYS A 319
LEU A  99
ALA A 321
LEU A 323
 None
 1.19A 6gnrB-2h8oA:
undetectable		 6gnrB-2h8oA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 2h8o GERANYLTRANSTRANSFER
ASE
(Agrobacterium
fabrum) 		5 / 9 ILE A 165
ALA A 112
GLY A 111
LEU A 114
GLY A  84
 None
 1.28A 6nm4B-2h8oA:
undetectable		 6nm4B-2h8oA:
19.23