SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2h9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LYS A 373
LEU A 179
GLU A 361
ALA A 374
 None
 1.18A 1etb1-2h9fA:
undetectable		 1etb1-2h9fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 334
ILE A 218
THR A 220
MET A 316
 None
 1.27A 1kglA-2h9fA:
undetectable		 1kglA-2h9fA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 322
ALA A 321
HIS A 351
 None
 0.78A 1q23C-2h9fA:
undetectable		 1q23C-2h9fA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  21
LEU A 107
SER A 108
LEU A  14
LEU A  74
 None
 1.15A 1ya4B-2h9fA:
undetectable		 1ya4B-2h9fA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ILE A   9
ARG A  25
ILE A  73
PHE A  44
 None
SO4  A 402 (-3.3A)
None
None
 0.99A 2q72A-2h9fA:
undetectable		 2q72A-2h9fA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  21
ALA A  11
VAL A 388
ILE A  48
 None
 0.81A 3a2qA-2h9fA:
undetectable		 3a2qA-2h9fA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 110
ALA A 115
VAL A 134
ILE A 174
 None
 0.75A 3a2qA-2h9fA:
undetectable		 3a2qA-2h9fA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  17
ALA A 147
ILE A 145
LEU A  74
VAL A  72
 None
 0.90A 3adxB-2h9fA:
undetectable		 3adxB-2h9fA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 371
GLY A 325
THR A 326
ALA A 329
 None
 0.57A 3aruA-2h9fA:
undetectable		 3aruA-2h9fA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 THR A  68
TYR A  13
VAL A  47
GLY A  62
GLY A  60
 None
 1.30A 3ixlA-2h9fA:
undetectable		 3ixlA-2h9fA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 339
LEU A 302
ALA A 279
THR A 220
ALA A 323
 None
 0.99A 4j14A-2h9fA:
undetectable		 4j14A-2h9fA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  40
TRP A 100
ILE A  73
 None
 0.92A 4mwxA-2h9fA:
undetectable		 4mwxA-2h9fA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 327
ALA A 328
ALA A 282
LEU A 337
 None
 0.65A 4v1fA-2h9fA:
undetectable
4v1fB-2h9fA:
undetectable		 4v1fA-2h9fA:
12.94
4v1fB-2h9fA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 103
SER A 108
ARG A 378
 None
 0.84A 5b2qA-2h9fA:
undetectable		 5b2qA-2h9fA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 328
ALA A 346
GLY A 341
GLY A 340
ALA A 339
 None
GOL  A 404 (-4.4A)
None
None
None
 1.00A 5lf3K-2h9fA:
undetectable
5lf3L-2h9fA:
undetectable		 5lf3K-2h9fA:
20.60
5lf3L-2h9fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 328
ALA A 346
GLY A 341
GLY A 340
ALA A 339
 None
GOL  A 404 (-4.4A)
None
None
None
 0.99A 5lf3Y-2h9fA:
undetectable
5lf3Z-2h9fA:
undetectable		 5lf3Y-2h9fA:
20.60
5lf3Z-2h9fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 328
ALA A 346
GLY A 341
GLY A 340
ALA A 339
 None
GOL  A 404 (-4.4A)
None
None
None
 0.95A 5lf7K-2h9fA:
undetectable
5lf7L-2h9fA:
undetectable		 5lf7K-2h9fA:
20.60
5lf7L-2h9fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 328
ALA A 346
GLY A 341
GLY A 340
ALA A 339
 None
GOL  A 404 (-4.4A)
None
None
None
 0.94A 5lf7Y-2h9fA:
undetectable
5lf7Z-2h9fA:
undetectable		 5lf7Y-2h9fA:
20.60
5lf7Z-2h9fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 112
ARG A 125
VAL A  84
ASP A  83
 None
 1.08A 5vlmA-2h9fA:
undetectable		 5vlmA-2h9fA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  21
GLY A 110
GLY A  16
ALA A 147
ALA A 111
 None
 1.03A 5x7fA-2h9fA:
undetectable		 5x7fA-2h9fA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 210
VAL A 198
ASP A 200
 None
 0.21A 6fgdA-2h9fA:
undetectable		 6fgdA-2h9fA:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 328
ALA A 346
GLY A 341
GLY A 340
ALA A 339
 None
GOL  A 404 (-4.4A)
None
None
None
 0.94A 6hwdK-2h9fA:
undetectable
6hwdL-2h9fA:
undetectable		 6hwdK-2h9fA:
12.36
6hwdL-2h9fA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2h9f HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 328
ALA A 346
GLY A 341
GLY A 340
ALA A 339
 None
GOL  A 404 (-4.4A)
None
None
None
 0.94A 6hwdY-2h9fA:
undetectable
6hwdZ-2h9fA:
undetectable		 6hwdY-2h9fA:
12.36
6hwdZ-2h9fA:
11.88