SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2haj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.79A 1v54C-2hajA:
undetectable
1v54J-2hajA:
undetectable		 1v54C-2hajA:
19.01
1v54J-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.78A 1v54P-2hajA:
undetectable
1v54W-2hajA:
undetectable		 1v54P-2hajA:
19.01
1v54W-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.78A 2dyrC-2hajA:
undetectable
2dyrJ-2hajA:
undetectable		 2dyrC-2hajA:
19.01
2dyrJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.79A 2dyrP-2hajA:
undetectable
2dyrW-2hajA:
undetectable		 2dyrP-2hajA:
19.01
2dyrW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.81A 2eikC-2hajA:
undetectable
2eikJ-2hajA:
undetectable		 2eikC-2hajA:
19.01
2eikJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.79A 2eikP-2hajA:
undetectable
2eikW-2hajA:
undetectable		 2eikP-2hajA:
19.01
2eikW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.77A 2eilC-2hajA:
undetectable
2eilJ-2hajA:
undetectable		 2eilC-2hajA:
19.01
2eilJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.82A 2eilP-2hajA:
undetectable
2eilW-2hajA:
undetectable		 2eilP-2hajA:
19.01
2eilW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.79A 2eimP-2hajA:
undetectable
2eimW-2hajA:
undetectable		 2eimP-2hajA:
19.01
2eimW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 6 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.88A 3abkP-2hajA:
undetectable
3abkW-2hajA:
undetectable		 3abkP-2hajA:
19.01
3abkW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.95A 3ag2P-2hajA:
undetectable
3ag2W-2hajA:
undetectable		 3ag2P-2hajA:
19.01
3ag2W-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.78A 3ag4C-2hajA:
undetectable
3ag4J-2hajA:
undetectable		 3ag4C-2hajA:
19.01
3ag4J-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.77A 3ag4P-2hajA:
undetectable
3ag4W-2hajA:
undetectable		 3ag4P-2hajA:
19.01
3ag4W-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.83A 3asnC-2hajA:
undetectable
3asnJ-2hajA:
undetectable		 3asnC-2hajA:
19.01
3asnJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.78A 3asnP-2hajA:
undetectable
3asnW-2hajA:
undetectable		 3asnP-2hajA:
19.01
3asnW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 8 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.84A 3asoC-2hajA:
undetectable
3asoJ-2hajA:
undetectable		 3asoC-2hajA:
19.01
3asoJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.80A 3asoP-2hajA:
undetectable
3asoW-2hajA:
undetectable		 3asoP-2hajA:
19.01
3asoW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 5 LEU A 464
LEU A 467
LEU A 539
SER A 538
 None
 1.01A 3vhuA-2hajA:
undetectable		 3vhuA-2hajA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 6 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.96A 3wg7P-2hajA:
undetectable
3wg7W-2hajA:
undetectable		 3wg7P-2hajA:
19.01
3wg7W-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.81A 3x2qC-2hajA:
undetectable
3x2qJ-2hajA:
undetectable		 3x2qC-2hajA:
19.01
3x2qJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.92A 3x2qP-2hajA:
undetectable
3x2qW-2hajA:
undetectable		 3x2qP-2hajA:
19.01
3x2qW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2haj DNA PRIMASE
(Escherichia
coli) 		3 / 3 PRO A 480
LEU A 479
HIS A 541
 None
 0.52A 4pevA-2hajA:
undetectable		 4pevA-2hajA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.87A 5b1aC-2hajA:
undetectable
5b1aJ-2hajA:
undetectable		 5b1aC-2hajA:
19.01
5b1aJ-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.88A 5b1aP-2hajA:
undetectable
5b1aW-2hajA:
undetectable		 5b1aP-2hajA:
19.01
5b1aW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.85A 5iy5C-2hajA:
undetectable
5iy5J-2hajA:
undetectable		 5iy5C-2hajA:
18.08
5iy5J-2hajA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 5 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.82A 5x19C-2hajA:
undetectable
5x19J-2hajA:
undetectable		 5x19C-2hajA:
19.01
5x19J-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.78A 5x1fP-2hajA:
undetectable
5x1fW-2hajA:
undetectable		 5x1fP-2hajA:
19.01
5x1fW-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.72A 5z84C-2hajA:
undetectable
5z84J-2hajA:
undetectable		 5z84C-2hajA:
19.01
5z84J-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.73A 5z85C-2hajA:
undetectable
5z85J-2hajA:
undetectable		 5z85C-2hajA:
19.01
5z85J-2hajA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2haj DNA PRIMASE
(Escherichia
coli) 		4 / 7 LEU A 454
PHE A 535
LEU A 539
PHE A 543
 None
 0.70A 5zcoC-2hajA:
undetectable
5zcoJ-2hajA:
undetectable		 5zcoC-2hajA:
19.01
5zcoJ-2hajA:
16.89