SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 ALA A 639
GLU A 419
LEU A 638
VAL A 587
 None
 0.80A 1hk2A-2hauA:
undetectable		 1hk2A-2hauA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 12 ILE A 462
PHE A 532
ALA A 428
LEU A 564
LEU A 444
 None
 1.19A 1og5B-2hauA:
undetectable		 1og5B-2hauA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 12 ASN A 268
ALA A  59
VAL A  81
ALA A  82
PHE A 295
 None
 1.33A 1udtA-2hauA:
undetectable		 1udtA-2hauA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 5 LEU A 293
LEU A 294
LEU A 267
MET A  26
 None
 1.12A 2oaxF-2hauA:
undetectable		 2oaxF-2hauA:
16.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 LEU A 641
TYR A 650
GLY A 652
 None
 0.26A 2ocuA-2hauA:
25.1		 2ocuA-2hauA:
32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 8 ALA A 322
ILE A 132
ILE A 130
HIS A 119
 None
 1.05A 2zmaA-2hauA:
undetectable		 2zmaA-2hauA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 GLU A 351
SER A 390
VAL A 587
 None
 0.80A 3eeoA-2hauA:
undetectable		 3eeoA-2hauA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 ILE A 130
TYR A 319
THR A 321
GLY A  65
 None
 1.01A 3gssB-2hauA:
undetectable		 3gssB-2hauA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 ASP A 163
ASP A 166
PRO A 168
GLN A 169
 None
 1.18A 3l2vA-2hauA:
undetectable		 3l2vA-2hauA:
20.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 7 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
 None
 0.74A 3tajA-2hauA:
25.2		 3tajA-2hauA:
32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 LYS A 569
PRO A 570
LEU A 561
 None
 0.84A 3tpxE-2hauA:
undetectable		 3tpxE-2hauA:
9.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 5 GLY A 425
PRO A 583
ASN A 584
TYR A 650
 None
 0.77A 3u8qA-2hauA:
27.0		 3u8qA-2hauA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 6 THR A 457
TYR A 655
HIS A 585
TYR A 426
 CIT  A9202 (-3.9A)
None
CIT  A9202 (-4.0A)
CIT  A9202 (-4.5A)
 1.31A 4df2A-2hauA:
undetectable		 4df2A-2hauA:
20.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 6 GLY A 425
PRO A 583
GLY A 652
GLU A 654
TYR A 655
 None
 0.93A 4dxuA-2hauA:
26.9		 4dxuA-2hauA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 9 GLY A 425
PRO A 583
TYR A 650
GLY A 652
TYR A 655
 None
 0.71A 4fimA-2hauA:
26.7		 4fimA-2hauA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 6 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
 None
 0.74A 4fjpA-2hauA:
26.9		 4fjpA-2hauA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 7 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
 None
 0.65A 4forA-2hauA:
25.7		 4forA-2hauA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 PRO A 583
TYR A 650
GLY A 652
 None
 0.51A 4g2zA-2hauA:
26.9		 4g2zA-2hauA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 ILE A 130
LEU A 134
HIS A 242
ALA A 244
 None
 0.63A 4g77A-2hauA:
25.5		 4g77A-2hauA:
32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 GLU A 419
ARG A 602
HIS A 606
 None
 0.87A 4kf9A-2hauA:
undetectable		 4kf9A-2hauA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 8 PHE A 153
VAL A 202
ASP A 201
ALA A  99
 None
 0.83A 4m48A-2hauA:
undetectable		 4m48A-2hauA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 9 VAL A 202
ALA A 203
GLY A 114
SER A 157
GLY A 200
 None
 1.20A 4mmfA-2hauA:
undetectable		 4mmfA-2hauA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		5 / 9 VAL A 202
ALA A 203
GLY A 114
SER A 157
GLY A 200
 None
 1.22A 4mmfB-2hauA:
undetectable		 4mmfB-2hauA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 VAL A 431
LEU A 561
VAL A 429
 None
 0.53A 4wq4A-2hauA:
undetectable		 4wq4A-2hauA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 5 ALA A 673
HIS A 207
PRO A 679
PHE A  94
 None
 1.26A 4ze2A-2hauA:
undetectable		 4ze2A-2hauA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 ALA A 322
ASN A 325
LEU A 326
 None
 0.51A 5i1oA-2hauA:
undetectable		 5i1oA-2hauA:
4.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		3 / 3 GLY A  34
GLN A 269
LYS A   4
 None
 0.97A 5imsB-2hauA:
undetectable		 5imsB-2hauA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 7 ALA A 453
GLY A 516
GLY A 519
ASN A 461
 None
 0.82A 5ybbB-2hauA:
undetectable		 5ybbB-2hauA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2hau SEROTRANSFERRIN
(Homo
sapiens) 		4 / 8 ILE A 263
VAL A 252
ILE A  52
TYR A  45
 None
 1.04A 6cduG-2hauA:
undetectable
6cduH-2hauA:
undetectable		 6cduG-2hauA:
19.64
6cduH-2hauA:
19.64