SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2hay PUTATIVE
NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Streptococcus
pyogenes) 		3 / 3 ALA A  38
THR A 155
PHE A  53
 None
 0.77A 2c6nB-2hayA:
undetectable		 2c6nB-2hayA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 2hay PUTATIVE
NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Streptococcus
pyogenes) 		4 / 4 LEU A 117
ARG A 104
LEU A 103
ALA A  97
 None
 1.15A 3b9mA-2hayA:
2.4		 3b9mA-2hayA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 2hay PUTATIVE
NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Streptococcus
pyogenes) 		6 / 12 ARG A 104
SER A 101
LEU A 102
ILE A  98
ALA A  91
THR A 141
 None
 1.46A 5veuH-2hayA:
undetectable		 5veuH-2hayA:
19.58