SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 4 ARG A 144
ALA A 143
ALA A 152
GLU A 150
 None
 1.12A 1e7bA-2hboA:
undetectable		 1e7bA-2hboA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 4 ARG A 144
ALA A 143
ALA A 152
GLU A 150
 None
 1.12A 1e7bB-2hboA:
undetectable		 1e7bB-2hboA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 5 ARG A 144
ALA A 143
ALA A 152
GLU A 150
 None
 1.12A 1e7cA-2hboA:
undetectable		 1e7cA-2hboA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 8 GLY A  62
GLY A  63
MET A  64
LEU A  65
 None
 0.55A 1qzzA-2hboA:
undetectable		 1qzzA-2hboA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 8 GLY A 122
CYH A  60
MET A  64
PHE A  26
 None
 1.05A 3ko0D-2hboA:
undetectable
3ko0E-2hboA:
undetectable		 3ko0D-2hboA:
18.99
3ko0E-2hboA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 8 GLY A 134
CYH A  60
MET A  64
PHE A  26
 EDO  A 159 (-3.5A)
None
None
None
 1.05A 3ko0D-2hboA:
undetectable
3ko0E-2hboA:
undetectable		 3ko0D-2hboA:
18.99
3ko0E-2hboA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		4 / 7 ARG A 129
ALA A 126
TRP A 103
ALA A  98
 None
 1.24A 3tx2A-2hboA:
undetectable		 3tx2A-2hboA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2hbo HYPOTHETICAL PROTEIN
(NP_422103.1)
(Caulobacter
vibrioides) 		5 / 12 GLY A 136
LEU A  33
VAL A 104
GLY A 106
ILE A 124
 None
 0.81A 5vopA-2hboA:
undetectable		 5vopA-2hboA:
22.07