SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 11 MET X  55
LEU X 108
LEU X 116
ILE X  63
TRP X  19
 None
 1.09A 2qd3A-2hczX:
undetectable		 2qd3A-2hczX:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 7 ILE X 148
PHE X 150
ARG X 213
MET X 177
 None
 1.11A 2zxwN-2hczX:
undetectable
2zxwW-2hczX:
undetectable		 2zxwN-2hczX:
17.97
2zxwW-2hczX:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 7 ILE X 148
PHE X 150
ARG X 213
MET X 177
 None
 1.06A 3ag2N-2hczX:
undetectable
3ag2W-2hczX:
undetectable		 3ag2N-2hczX:
17.97
3ag2W-2hczX:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 7 ILE X 148
PHE X 150
ARG X 213
MET X 177
 None
 1.05A 3ag4N-2hczX:
undetectable
3ag4W-2hczX:
undetectable		 3ag4N-2hczX:
17.97
3ag4W-2hczX:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 7 ILE X 152
LYS X 225
PHE X 210
GLY X 208
 None
 1.05A 3sj0X-2hczX:
undetectable		 3sj0X-2hczX:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 9 ILE X 152
LEU X 161
LYS X 225
PHE X 210
GLY X 208
 None
 1.01A 3sj4X-2hczX:
undetectable		 3sj4X-2hczX:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 8 GLY X 195
ALA X 196
GLY X  71
ILE X  93
 None
 0.69A 3so9A-2hczX:
undetectable		 3so9A-2hczX:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		6 / 11 GLY X 195
ALA X 196
VAL X 168
GLY X 172
GLY X  71
ILE X  93
 None
 1.07A 3ufnA-2hczX:
undetectable		 3ufnA-2hczX:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		3 / 3 TYR X  74
ASP X 173
ASP X 170
 None
 0.73A 4a6eA-2hczX:
undetectable		 4a6eA-2hczX:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 6 PHE X 135
ALA X  22
GLY X   8
PRO X   9
 None
 0.87A 4dubA-2hczX:
undetectable		 4dubA-2hczX:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 6 PHE X 135
ALA X  22
GLY X   8
PRO X   9
 None
 0.88A 4dubB-2hczX:
undetectable		 4dubB-2hczX:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 7 ILE X 152
LEU X 161
LYS X 225
PHE X 210
GLY X 208
 None
 1.10A 4hajA-2hczX:
undetectable		 4hajA-2hczX:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 8 ILE X 152
LEU X 161
LYS X 225
PHE X 210
GLY X 208
 None
 1.02A 4hb8A-2hczX:
undetectable		 4hb8A-2hczX:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		3 / 3 LYS X 221
ARG X 213
TRP X 187
 None
 1.19A 4i90A-2hczX:
undetectable		 4i90A-2hczX:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 12 GLN X 243
TYR X  52
GLY X 172
TYR X  92
ALA X 169
 None
 1.25A 5e3iA-2hczX:
undetectable		 5e3iA-2hczX:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 11 GLN X 243
TYR X  52
GLY X 172
TYR X  92
ALA X 169
 None
 1.25A 5e3iB-2hczX:
undetectable		 5e3iB-2hczX:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		4 / 8 VAL X 175
ILE X 174
ILE X 223
PHE X 244
 None
 0.69A 5hw8H-2hczX:
undetectable		 5hw8H-2hczX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 12 ALA X 169
GLY X 145
ASP X 173
ARG X 137
TYR X  15
 None
 1.31A 5zvgA-2hczX:
undetectable		 5zvgA-2hczX:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 2hcz BETA-EXPANSIN 1A
(Zea
mays) 		5 / 12 ALA X 169
GLY X 145
ASP X 173
ARG X 137
TYR X  15
 None
 1.29A 5zvgB-2hczX:
undetectable		 5zvgB-2hczX:
20.05