SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 2hd7 TWINFILIN-1
(Mus
musculus) 		4 / 7 LEU A 198
LEU A 193
SER A 252
SER A 194
 None
 1.08A 1dvxA-2hd7A:
undetectable		 1dvxA-2hd7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 GLN A 202
TYR A 272
ARG A 269
 None
 0.95A 1gtbA-2hd7A:
undetectable		 1gtbA-2hd7A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 LEU A 190
VAL A 283
LEU A 280
 None
 0.42A 1mz9B-2hd7A:
undetectable		 1mz9B-2hd7A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.72A 1rjoA-2hd7A:
undetectable		 1rjoA-2hd7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.70A 1w2zB-2hd7A:
undetectable		 1w2zB-2hd7A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.69A 1w2zC-2hd7A:
undetectable		 1w2zC-2hd7A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.67A 1w2zD-2hd7A:
undetectable		 1w2zD-2hd7A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.72A 2oqeA-2hd7A:
undetectable		 2oqeA-2hd7A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.71A 2oqeB-2hd7A:
undetectable		 2oqeB-2hd7A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.71A 2oqeD-2hd7A:
undetectable		 2oqeD-2hd7A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2hd7 TWINFILIN-1
(Mus
musculus) 		3 / 3 HIS A 243
HIS A 313
HIS A 245
 None
 0.73A 2oqeF-2hd7A:
undetectable		 2oqeF-2hd7A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 2hd7 TWINFILIN-1
(Mus
musculus) 		4 / 8 ILE A 256
HIS A 237
LEU A 225
GLY A 300
 None
 0.95A 2vdbA-2hd7A:
undetectable		 2vdbA-2hd7A:
13.02