SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		4 / 8 TYR A 118
PHE A 120
MET A 121
THR A 104
 None
None
None
PO4  A 209 (-3.7A)
 0.87A 1ea1A-2hdoA:
undetectable		 1ea1A-2hdoA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		3 / 3 LEU A 141
PRO A 140
LEU A 144
 None
 0.55A 1hrkA-2hdoA:
3.3		 1hrkA-2hdoA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		5 / 8 LEU A  98
GLN A   4
PHE A 207
LEU A  94
PHE A  91
 None
 1.37A 2eilP-2hdoA:
undetectable
2eilW-2hdoA:
undetectable		 2eilP-2hdoA:
23.44
2eilW-2hdoA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		3 / 3 LEU A 206
LEU A 100
PHE A 197
 None
 0.53A 2pgrA-2hdoA:
undetectable		 2pgrA-2hdoA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		4 / 4 VAL A  24
VAL A  73
TYR A  70
GLN A  69
 None
PO4  A 210 ( 4.3A)
None
None
 1.49A 5qgqA-2hdoA:
undetectable		 5qgqA-2hdoA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		4 / 6 GLN A   4
PHE A 207
LEU A  94
PHE A  91
 None
 0.98A 5z84P-2hdoA:
undetectable
5z84W-2hdoA:
undetectable		 5z84P-2hdoA:
23.44
5z84W-2hdoA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		4 / 6 GLN A   4
PHE A 207
LEU A  94
PHE A  91
 None
 0.99A 5z85P-2hdoA:
undetectable
5z85W-2hdoA:
undetectable		 5z85P-2hdoA:
23.44
5z85W-2hdoA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		4 / 6 GLN A   4
PHE A 207
LEU A  94
PHE A  91
 None
 1.01A 5z86P-2hdoA:
undetectable
5z86W-2hdoA:
undetectable		 5z86P-2hdoA:
23.44
5z86W-2hdoA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hdo PHOSPHOGLYCOLATE
PHOSPHATASE
(Lactobacillus
plantarum) 		4 / 6 GLN A   4
PHE A 207
LEU A  94
PHE A  91
 None
 0.99A 5zcpP-2hdoA:
undetectable
5zcpW-2hdoA:
undetectable		 5zcpP-2hdoA:
23.44
5zcpW-2hdoA:
16.92