SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2he9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		6 / 12 SER A 145
ILE A  13
ILE A 153
ILE A  73
PHE A  64
VAL A 143
 None
 1.34A 1qhsA-2he9A:
undetectable		 1qhsA-2he9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 109
PHE A  25
ILE A 150
SER A 121
VAL A 170
 None
 1.20A 2po5A-2he9A:
undetectable		 2po5A-2he9A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 6 PHE A  25
PHE A  39
GLY A  75
GLY A  76
 None
 0.85A 2qr2A-2he9A:
undetectable
2qr2B-2he9A:
undetectable		 2qr2A-2he9A:
21.05
2qr2B-2he9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 5 GLY A  75
GLY A  76
PHE A  25
PHE A  39
 None
 0.78A 2qr2A-2he9A:
undetectable
2qr2B-2he9A:
undetectable		 2qr2A-2he9A:
21.05
2qr2B-2he9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 8 PHE A  25
PHE A  39
GLY A  75
GLY A  76
 None
 0.74A 2qx4A-2he9A:
undetectable
2qx4B-2he9A:
undetectable		 2qx4A-2he9A:
21.05
2qx4B-2he9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 6 PHE A  25
PHE A  39
GLY A  75
GLY A  76
 None
 0.73A 2qx6A-2he9A:
undetectable
2qx6B-2he9A:
undetectable		 2qx6A-2he9A:
21.05
2qx6B-2he9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		5 / 11 ALA A 106
LEU A 142
VAL A 143
PHE A 147
THR A 126
 None
 1.31A 3jw5A-2he9A:
undetectable		 3jw5A-2he9A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		3 / 3 GLY A 174
ILE A 171
VAL A 170
 None
 0.51A 3nv6A-2he9A:
undetectable		 3nv6A-2he9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 5 TYR A  59
VAL A 170
SER A  62
GLY A  75
 None
 1.35A 3v4tA-2he9A:
undetectable
3v4tD-2he9A:
undetectable		 3v4tA-2he9A:
17.20
3v4tD-2he9A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 109
PHE A  25
ILE A 150
SER A 121
VAL A 170
 None
 1.37A 3w1wA-2he9A:
undetectable		 3w1wA-2he9A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 4 LEU A 142
ILE A 125
GLY A 141
PHE A  25
 None
 1.14A 4dc3A-2he9A:
undetectable		 4dc3A-2he9A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 6 ARG A 114
GLY A 115
GLN A  74
MET A  72
 None
 1.21A 4g0vB-2he9A:
undetectable		 4g0vB-2he9A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		4 / 7 GLY A  76
GLN A 122
SER A  62
HIS A  65
 None
 1.17A 4ws0A-2he9A:
undetectable		 4ws0A-2he9A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 120
ILE A  89
ASN A 113
PHE A  39
LEU A 109
 None
 1.06A 5fa8A-2he9A:
undetectable		 5fa8A-2he9A:
23.00