SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.31A 1d4fC-2hfqA:
undetectable		 1d4fC-2hfqA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.20A 1v8bA-2hfqA:
undetectable		 1v8bA-2hfqA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.17A 1v8bB-2hfqA:
undetectable		 1v8bB-2hfqA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.19A 1v8bC-2hfqA:
undetectable		 1v8bC-2hfqA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.18A 1v8bD-2hfqA:
undetectable		 1v8bD-2hfqA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.17A 2zj0A-2hfqA:
undetectable		 2zj0A-2hfqA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.19A 3ce6A-2hfqA:
undetectable		 3ce6A-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.19A 3ce6C-2hfqA:
undetectable		 3ce6C-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.17A 3glqA-2hfqA:
undetectable		 3glqA-2hfqA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.21A 3glqB-2hfqA:
undetectable		 3glqB-2hfqA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.24A 3n58A-2hfqA:
undetectable		 3n58A-2hfqA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.22A 4lvcA-2hfqA:
undetectable		 4lvcA-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.21A 4lvcB-2hfqA:
undetectable		 4lvcB-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.17A 4lvcC-2hfqA:
undetectable		 4lvcC-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.19A 4pfjA-2hfqA:
undetectable		 4pfjA-2hfqA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.14A 4pgfA-2hfqA:
undetectable		 4pgfA-2hfqA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.20A 5axaA-2hfqA:
undetectable		 5axaA-2hfqA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.20A 5axaC-2hfqA:
undetectable		 5axaC-2hfqA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5hm8A-2hfqA:
undetectable		 5hm8A-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5hm8B-2hfqA:
undetectable		 5hm8B-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.15A 5hm8C-2hfqA:
undetectable		 5hm8C-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5hm8D-2hfqA:
undetectable		 5hm8D-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5hm8E-2hfqA:
undetectable		 5hm8E-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.15A 5hm8F-2hfqA:
undetectable		 5hm8F-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5hm8G-2hfqA:
undetectable		 5hm8G-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5hm8H-2hfqA:
undetectable		 5hm8H-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.21A 5m5kA-2hfqA:
undetectable		 5m5kA-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.21A 5m5kB-2hfqA:
undetectable		 5m5kB-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.22A 5m5kC-2hfqA:
undetectable		 5m5kC-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5m66A-2hfqA:
undetectable		 5m66A-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.21A 5m66B-2hfqA:
undetectable		 5m66B-2hfqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.17A 5utuF-2hfqA:
undetectable		 5utuF-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 5utuH-2hfqA:
undetectable		 5utuH-2hfqA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.23A 5v96A-2hfqA:
undetectable		 5v96A-2hfqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.22A 5v96B-2hfqA:
undetectable		 5v96B-2hfqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.21A 5v96C-2hfqA:
undetectable		 5v96C-2hfqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.24A 5v96D-2hfqA:
undetectable		 5v96D-2hfqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 6aphA-2hfqA:
undetectable		 6aphA-2hfqA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.16A 6gbnA-2hfqA:
undetectable		 6gbnA-2hfqA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.18A 6gbnB-2hfqA:
undetectable		 6gbnB-2hfqA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 2hfq HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A  40
LYS A  80
GLY A  15
HIS A  16
MET A  18
 None
 1.15A 6gbnD-2hfqA:
undetectable		 6gbnD-2hfqA:
14.21