SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hgm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 2hgm HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN F
(Homo
sapiens) 		4 / 6 SER A 104
SER A 187
ASP A 110
ASP A 106
 None
 1.15A 2j2pE-2hgmA:
undetectable
2j2pF-2hgmA:
undetectable		 2j2pE-2hgmA:
20.64
2j2pF-2hgmA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2hgm HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN F
(Homo
sapiens) 		4 / 5 PHE A 130
PHE A 131
PHE A 159
VAL A 183
 None
 1.25A 2lh6A-2hgmA:
undetectable		 2lh6A-2hgmA:
23.23