SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hgn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2hgn HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN F
(Homo
sapiens) 		4 / 8 ASP A 304
ILE A 305
PHE A 308
VAL A 291
 None
 0.91A 4acbB-2hgnA:
undetectable
4acbC-2hgnA:
undetectable		 4acbB-2hgnA:
13.61
4acbC-2hgnA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 2hgn HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN F
(Homo
sapiens) 		3 / 3 MET A 293
GLN A 353
TYR A 298
 None
 0.97A 4udcA-2hgnA:
undetectable		 4udcA-2hgnA:
17.39