SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hh6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I00_B_D16B409_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 9	ILE A 38 ASP A 63 LEU A 62 GLY A 59 PHE A 58	None	1.30A	1i00B-2hh6A: undetectable	1i00B-2hh6A: 15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TSR_C_D16C509_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 10	ILE A 38 ASP A 63 LEU A 62 GLY A 59 PHE A 58	None	1.25A	2tsrC-2hh6A: undetectable	2tsrC-2hh6A: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_A_D16A402_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 7	ILE A 38 ASP A 63 LEU A 62 GLY A 59 PHE A 58	None	1.30A	4iqqA-2hh6A: undetectable	4iqqA-2hh6A: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_C_D16C402_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 7	ILE A 38 ASP A 63 LEU A 62 GLY A 59 PHE A 58	None	1.11A	4iqqC-2hh6A: undetectable	4iqqC-2hh6A: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_D_D16D402_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 8	ILE A 38 ASP A 63 LEU A 62 GLY A 59 PHE A 58	None	1.27A	4iqqD-2hh6A: undetectable	4iqqD-2hh6A: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J7W_C_MTXC402_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 12	LEU A 90 ILE A 61 LEU A 78 PHE A 86 ALA A 69	None	1.30A	5j7wC-2hh6A: undetectable	5j7wC-2hh6A: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NOO_D_D16D402_1 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 8	ILE A 38 ASP A 63 LEU A 62 GLY A 59 PHE A 58	None	1.28A	5nooD-2hh6A: undetectable	5nooD-2hh6A: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QYA_B_FOZB401_0 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 12	LEU A 90 ILE A 61 LEU A 78 PHE A 86 ALA A 69	None	1.22A	6qyaB-2hh6A: undetectable	6qyaB-2hh6A: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QYA_D_FOZD401_0 (THYMIDYLATE SYNTHASE)	2hh6	BH3980 PROTEIN (Bacillus halodurans)	5 / 12	LEU A 90 ILE A 61 LEU A 78 PHE A 86 ALA A 69	None	1.23A	6qyaD-2hh6A: undetectable	6qyaD-2hh6A: 16.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1I00_B_D16B409_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"ILE A  38;ASP A  63;LEU A  62;GLY A  59;PHE A  58","None","1.30A","1i00B-2hh6A:undetectable","1i00B-2hh6A:15.41"],["2TSR_C_D16C509_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"ILE A  38;ASP A  63;LEU A  62;GLY A  59;PHE A  58","None","1.25A","2tsrC-2hh6A:undetectable","2tsrC-2hh6A:19.25"],["4IQQ_A_D16A402_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"ILE A  38;ASP A  63;LEU A  62;GLY A  59;PHE A  58","None","1.30A","4iqqA-2hh6A:undetectable","4iqqA-2hh6A:19.23"],["4IQQ_C_D16C402_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"ILE A  38;ASP A  63;LEU A  62;GLY A  59;PHE A  58","None","1.11A","4iqqC-2hh6A:undetectable","4iqqC-2hh6A:19.23"],["4IQQ_D_D16D402_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"ILE A  38;ASP A  63;LEU A  62;GLY A  59;PHE A  58","None","1.27A","4iqqD-2hh6A:undetectable","4iqqD-2hh6A:19.23"],["5J7W_C_MTXC402_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"LEU A  90;ILE A  61;LEU A  78;PHE A  86;ALA A  69","None","1.30A","5j7wC-2hh6A:undetectable","5j7wC-2hh6A:16.56"],["5NOO_D_D16D402_1","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"ILE A  38;ASP A  63;LEU A  62;GLY A  59;PHE A  58","None","1.28A","5nooD-2hh6A:undetectable","5nooD-2hh6A:19.23"],["6QYA_B_FOZB401_0","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"LEU A  90;ILE A  61;LEU A  78;PHE A  86;ALA A  69","None","1.22A","6qyaB-2hh6A:undetectable","6qyaB-2hh6A:16.56"],["6QYA_D_FOZD401_0","THYMIDYLATE SYNTHASE","2hh6","BH3980 PROTEIN","Bacillus halodurans",5,"LEU A  90;ILE A  61;LEU A  78;PHE A  86;ALA A  69","None","1.23A","6qyaD-2hh6A:undetectable","6qyaD-2hh6A:16.56"]]