SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		6 / 12 LEU A  56
ALA A  83
ILE A 118
HIS A 103
ILE A 104
LEU A  91
 None
 1.06A 1tw4A-2hhzA:
1.7		 1tw4A-2hhzA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		5 / 12 LEU A  56
ILE A 118
HIS A 103
ILE A 104
LEU A  91
 None
 1.09A 1tw4B-2hhzA:
1.9		 1tw4B-2hhzA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		5 / 12 LEU A  56
ALA A  83
ILE A 118
HIS A 103
ILE A 104
 None
 1.08A 2jn3A-2hhzA:
2.6		 2jn3A-2hhzA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		5 / 12 LEU A  56
ALA A  83
ILE A 118
HIS A 103
LEU A  91
 None
 0.94A 2jn3A-2hhzA:
2.6		 2jn3A-2hhzA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		5 / 12 ILE A  42
ALA A  37
PHE A  18
GLY A  81
VAL A  62
 None
 0.98A 5i73A-2hhzA:
undetectable		 5i73A-2hhzA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		4 / 4 LEU A  21
ASP A  22
GLN A  55
VAL A  76
 None
None
PO4  A 150 ( 4.4A)
None
 1.44A 6bzoF-2hhzA:
undetectable		 6bzoF-2hhzA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2hhz PYRIDOXAMINE
5'-PHOSPHATE
OXIDASE-RELATED
(Streptococcus
suis) 		4 / 5 ARG A  84
ALA A  83
GLN A 117
ILE A 138
 None
 1.33A 6f6sA-2hhzA:
undetectable
6f6sB-2hhzA:
undetectable		 6f6sA-2hhzA:
16.33
6f6sB-2hhzA:
19.05