SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hi3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.92A 1v55C-2hi3A:
undetectable
1v55J-2hi3A:
undetectable		 1v55C-2hi3A:
13.41
1v55J-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.98A 1v55P-2hi3A:
undetectable
1v55W-2hi3A:
undetectable		 1v55P-2hi3A:
13.41
1v55W-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.99A 2dysC-2hi3A:
undetectable
2dysJ-2hi3A:
undetectable		 2dysC-2hi3A:
13.41
2dysJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.98A 2eijC-2hi3A:
undetectable
2eijJ-2hi3A:
undetectable		 2eijC-2hi3A:
13.41
2eijJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.98A 2eijP-2hi3A:
undetectable
2eijW-2hi3A:
undetectable		 2eijP-2hi3A:
13.41
2eijW-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.92A 2eikC-2hi3A:
undetectable
2eikJ-2hi3A:
undetectable		 2eikC-2hi3A:
13.41
2eikJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 8 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.92A 2eilC-2hi3A:
undetectable
2eilJ-2hi3A:
undetectable		 2eilC-2hi3A:
13.41
2eilJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 8 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.93A 2eilP-2hi3A:
undetectable
2eilW-2hi3A:
undetectable		 2eilP-2hi3A:
13.41
2eilW-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.89A 2eimC-2hi3A:
undetectable
2eimJ-2hi3A:
undetectable		 2eimC-2hi3A:
13.41
2eimJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.98A 2einC-2hi3A:
undetectable
2einJ-2hi3A:
undetectable		 2einC-2hi3A:
13.41
2einJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.94A 5b1aC-2hi3A:
undetectable
5b1aJ-2hi3A:
undetectable		 5b1aC-2hi3A:
13.41
5b1aJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.93A 5b1aP-2hi3A:
undetectable
5b1aW-2hi3A:
undetectable		 5b1aP-2hi3A:
13.41
5b1aW-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.96A 5b3sC-2hi3A:
undetectable
5b3sJ-2hi3A:
undetectable		 5b3sC-2hi3A:
13.41
5b3sJ-2hi3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 7 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 0.94A 5b3sP-2hi3A:
undetectable		 5b3sP-2hi3A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		3 / 3 ARG A  59
LEU A  55
PHE A  51
 None
 0.70A 6nknP-2hi3A:
undetectable		 6nknP-2hi3A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hi3 HOMEODOMAIN-ONLY
PROTEIN
(Mus
musculus) 		4 / 5 ARG A  59
LEU A  55
GLN A  53
PHE A  51
 None
 1.02A 6nmpP-2hi3A:
undetectable
6nmpW-2hi3A:
undetectable		 6nmpP-2hi3A:
13.41
6nmpW-2hi3A:
18.31