SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.94A 1c9sN-2hj0A:
undetectable
1c9sO-2hj0A:
undetectable		 1c9sN-2hj0A:
10.04
1c9sO-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.95A 1c9sP-2hj0A:
undetectable
1c9sQ-2hj0A:
undetectable		 1c9sP-2hj0A:
10.04
1c9sQ-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 GLY A 191
GLY A 168
HIS A  70
ALA A 178
ILE A 205
 None
 0.96A 1c9sL-2hj0A:
undetectable
1c9sV-2hj0A:
undetectable		 1c9sL-2hj0A:
10.04
1c9sV-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.97A 1gtfQ-2hj0A:
undetectable
1gtfR-2hj0A:
undetectable		 1gtfQ-2hj0A:
10.04
1gtfR-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.98A 1gtfS-2hj0A:
undetectable
1gtfT-2hj0A:
undetectable		 1gtfS-2hj0A:
10.04
1gtfT-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 1.03A 1gtnT-2hj0A:
undetectable
1gtnU-2hj0A:
undetectable		 1gtnT-2hj0A:
10.04
1gtnU-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 PHE A 405
ALA A 404
GLY A 149
ALA A 396
LEU A 372
 None
None
None
CIT  A 601 (-2.9A)
None
 1.44A 1jipA-2hj0A:
undetectable		 1jipA-2hj0A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 VAL A 428
LEU A 375
SER A 373
LEU A 372
THR A 430
 None
 1.02A 1kw0A-2hj0A:
undetectable		 1kw0A-2hj0A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 8 LEU A 463
ILE A 447
VAL A 440
ILE A 449
MET A 409
 None
 1.26A 1linA-2hj0A:
undetectable		 1linA-2hj0A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 VAL A 428
LEU A 375
SER A 373
LEU A 372
THR A 430
 None
 0.97A 1mmtA-2hj0A:
undetectable		 1mmtA-2hj0A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 6 PHE A 304
ALA A 305
LEU A 306
SER A 275
 None
 0.86A 1sbrA-2hj0A:
undetectable
1sbrB-2hj0A:
undetectable		 1sbrA-2hj0A:
17.94
1sbrB-2hj0A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 ASP A 402
GLY A 149
ILE A 432
ILE A 497
PRO A 434
 None
 0.87A 1sguB-2hj0A:
undetectable		 1sguB-2hj0A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 ASP A 402
GLY A 149
ILE A 432
ILE A 497
PRO A 434
 None
 1.06A 1sh9B-2hj0A:
undetectable		 1sh9B-2hj0A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.98A 1utdO-2hj0A:
undetectable
1utdP-2hj0A:
undetectable		 1utdO-2hj0A:
10.04
1utdP-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.99A 1utdP-2hj0A:
undetectable
1utdQ-2hj0A:
undetectable		 1utdP-2hj0A:
10.04
1utdQ-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 0.99A 1utdS-2hj0A:
undetectable
1utdT-2hj0A:
undetectable		 1utdS-2hj0A:
10.04
1utdT-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 GLY A 168
HIS A  70
ALA A 178
ILE A 205
GLY A 191
 None
 1.00A 1utdU-2hj0A:
undetectable
1utdV-2hj0A:
undetectable		 1utdU-2hj0A:
10.04
1utdV-2hj0A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 6 ILE A 134
VAL A 130
ILE A  87
ILE A  52
 None
 0.75A 1uwhA-2hj0A:
undetectable		 1uwhA-2hj0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 6 ILE A 134
VAL A 130
ILE A  87
ILE A  52
 None
 0.75A 1uwhB-2hj0A:
undetectable		 1uwhB-2hj0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 PHE A 274
VAL A 322
GLU A 319
LEU A 316
ARG A 292
 None
 1.13A 2bxfA-2hj0A:
undetectable		 2bxfA-2hj0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 PHE A 274
VAL A 322
GLU A 319
LEU A 316
ARG A 292
 None
 1.18A 2bxfB-2hj0A:
undetectable		 2bxfB-2hj0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 SER A 437
LEU A 306
GLY A 399
TYR A 192
ALA A 351
 None
 1.31A 2kceA-2hj0A:
undetectable		 2kceA-2hj0A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 HIS A 106
LEU A 126
GLY A 131
VAL A 143
ALA A 495
 None
 1.16A 2kceB-2hj0A:
undetectable		 2kceB-2hj0A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 ASN A 365
ILE A 497
ILE A 145
ASP A 402
ALA A 404
 None
 1.31A 2qmjA-2hj0A:
2.0		 2qmjA-2hj0A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 8 VAL A 428
SER A 147
VAL A 412
VAL A 385
 None
 1.28A 2y05A-2hj0A:
4.0
2y05B-2hj0A:
5.8		 2y05A-2hj0A:
20.62
2y05B-2hj0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 GLN A 202
SER A 172
ASN A 177
GLN A 222
TYR A 227
 None
 1.30A 3fsuA-2hj0A:
undetectable		 3fsuA-2hj0A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 8 ILE A 309
ALA A 305
PHE A 276
LEU A 317
 None
 0.96A 3hrdA-2hj0A:
undetectable
3hrdB-2hj0A:
undetectable		 3hrdA-2hj0A:
21.38
3hrdB-2hj0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 8 TYR A 247
ALA A 257
ALA A 261
THR A 265
 None
 0.88A 3khmA-2hj0A:
undetectable		 3khmA-2hj0A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 8 TYR A 247
ALA A 257
ALA A 261
THR A 265
 None
 0.92A 3l4dA-2hj0A:
undetectable		 3l4dA-2hj0A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 8 TYR A 247
ALA A 257
ALA A 261
THR A 265
 None
 0.90A 3l4dD-2hj0A:
undetectable		 3l4dD-2hj0A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 9 ILE A 497
ILE A 432
VAL A 508
THR A 387
ILE A 393
 None
 0.91A 3p4wB-2hj0A:
undetectable		 3p4wB-2hj0A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 ILE A 497
ILE A 432
VAL A 508
THR A 387
ILE A 393
 None
 0.91A 3p4wD-2hj0A:
undetectable		 3p4wD-2hj0A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 ILE A 497
ILE A 432
VAL A 508
THR A 387
ILE A 393
 None
 0.91A 3p4wE-2hj0A:
undetectable		 3p4wE-2hj0A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		3 / 4 SER A 335
GLY A 279
GLU A 253
 None
 0.68A 3raeA-2hj0A:
undetectable
3raeC-2hj0A:
undetectable		 3raeA-2hj0A:
25.48
3raeC-2hj0A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 7 GLY A 150
GLY A 149
ASN A 352
GLU A 498
 None
 0.97A 4fgkB-2hj0A:
2.3		 4fgkB-2hj0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 7 GLU A 376
ASP A 378
ASN A 382
ILE A 432
 None
 1.11A 4ii8A-2hj0A:
undetectable		 4ii8A-2hj0A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		3 / 3 LYS A  42
PRO A  43
SER A  44
 None
 0.49A 4k50I-2hj0A:
undetectable		 4k50I-2hj0A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 ILE A 497
ILE A 113
LEU A 109
GLY A 131
ASN A 429
 None
 1.16A 4o1eA-2hj0A:
undetectable		 4o1eA-2hj0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		3 / 3 ALA A 260
GLN A 277
GLY A 307
 None
 0.49A 4odoC-2hj0A:
undetectable		 4odoC-2hj0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 ILE A  67
ILE A 102
LEU A 109
PRO A 108
ILE A  97
 None
 1.06A 4p3qA-2hj0A:
undetectable		 4p3qA-2hj0A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 PHE A 331
GLY A 279
SER A 373
ILE A 309
LEU A 306
 CIT  A 601 (-4.4A)
None
None
None
None
 1.01A 4qdjA-2hj0A:
3.8		 4qdjA-2hj0A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 12 ASP A 402
SER A 147
THR A 157
ALA A 156
ALA A 154
 None
 1.35A 4u15B-2hj0A:
undetectable		 4u15B-2hj0A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 11 VAL A 412
PHE A 331
GLY A 399
GLY A 398
ILE A 432
 None
CIT  A 601 (-4.4A)
None
CIT  A 601 (-3.6A)
None
 1.32A 4zvmA-2hj0A:
2.5
4zvmB-2hj0A:
3.8		 4zvmA-2hj0A:
17.50
4zvmB-2hj0A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 5 PHE A 424
ASP A 378
PHE A 381
VAL A 441
 None
 1.20A 5a1rA-2hj0A:
undetectable		 5a1rA-2hj0A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 10 ALA A 169
ILE A 205
GLY A 191
ALA A 197
ASP A 224
 None
 1.37A 5ajqB-2hj0A:
undetectable		 5ajqB-2hj0A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 8 ILE A 432
VAL A 383
VAL A 263
ILE A 369
ASP A 439
 None
 1.47A 5hi2A-2hj0A:
undetectable		 5hi2A-2hj0A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		3 / 3 LYS A 114
LEU A  84
ILE A 121
 None
 0.58A 5kc4A-2hj0A:
undetectable		 5kc4A-2hj0A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		5 / 9 GLY A 180
ALA A 169
CYH A 187
GLY A 188
LEU A 339
 None
 1.02A 5vw4A-2hj0A:
undetectable		 5vw4A-2hj0A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		4 / 8 GLY A 180
CYH A 187
GLY A 188
LEU A 339
 None
 0.64A 5vw5A-2hj0A:
undetectable		 5vw5A-2hj0A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT
(Streptococcus
mutans) 		3 / 3 SER A 124
HIS A  71
TYR A 192
 CIT  A 601 (-2.8A)
CIT  A 601 (-3.8A)
None
 0.95A 5y2tA-2hj0A:
undetectable		 5y2tA-2hj0A:
undetectable