SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2hje AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ
(Vibrio
harveyi) 		4 / 8 LEU A 266
VAL A 211
LEU A 168
LEU A 192
 None
 0.95A 4l1xA-2hjeA:
undetectable		 4l1xA-2hjeA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2hje AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ
(Vibrio
harveyi) 		3 / 3 LEU A 224
PHE A 196
ILE A 225
 None
 0.67A 5dzk1-2hjeA:
undetectable
5dzkF-2hjeA:
undetectable
5dzkM-2hjeA:
undetectable		 5dzk1-2hjeA:
0.92
5dzkF-2hjeA:
25.00
5dzkM-2hjeA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 2hje AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ
(Vibrio
harveyi) 		5 / 12 ASP A 104
SER A  81
ILE A  84
LEU A 117
THR A 111
 None
 1.09A 5hi6B-2hjeA:
undetectable		 5hi6B-2hjeA:
23.35