SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 2hjn MAINTENANCE OF
PLOIDY PROTEIN MOB1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 283
THR A 134
VAL A 131
ALA A 260
 None
 1.08A 1fo4B-2hjnA:
undetectable		 1fo4B-2hjnA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2hjn MAINTENANCE OF
PLOIDY PROTEIN MOB1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 259
LEU A 279
VAL A 308
PHE A 289
CYH A 287
 None
 1.29A 2g70A-2hjnA:
undetectable		 2g70A-2hjnA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2hjn MAINTENANCE OF
PLOIDY PROTEIN MOB1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 259
LEU A 279
VAL A 308
PHE A 289
CYH A 287
 None
 1.31A 2g72A-2hjnA:
undetectable		 2g72A-2hjnA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6M_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2hjn MAINTENANCE OF
PLOIDY PROTEIN MOB1
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 189
LEU A 304
LEU A 279
ILE A 262
THR A 190
 None
 0.87A 5z6mA-2hjnA:
undetectable		 5z6mA-2hjnA:
18.60