SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 2hjv ATP-DEPENDENT RNA
HELICASE DBPA
(Bacillus
subtilis) 		4 / 7 ASP A 354
SER A 323
ARG A 327
LEU A 317
 None
 1.08A 2cdqB-2hjvA:
undetectable		 2cdqB-2hjvA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2hjv ATP-DEPENDENT RNA
HELICASE DBPA
(Bacillus
subtilis) 		5 / 10 LYS A 339
GLU A 216
GLU A 238
ILE A 341
ILE A 366
 None
 1.34A 2j9dD-2hjvA:
0.0
2j9dE-2hjvA:
0.0
2j9dF-2hjvA:
0.0		 2j9dD-2hjvA:
22.81
2j9dE-2hjvA:
22.81
2j9dF-2hjvA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2hjv ATP-DEPENDENT RNA
HELICASE DBPA
(Bacillus
subtilis) 		4 / 7 VAL A 234
ILE A 220
ILE A 366
ALA A 218
 None
 0.89A 4lv9B-2hjvA:
undetectable		 4lv9B-2hjvA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2hjv ATP-DEPENDENT RNA
HELICASE DBPA
(Bacillus
subtilis) 		4 / 6 TYR A 265
ASP A 233
ILE A 313
TYR A 315
 None
 1.17A 5igyA-2hjvA:
undetectable		 5igyA-2hjvA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2hjv ATP-DEPENDENT RNA
HELICASE DBPA
(Bacillus
subtilis) 		4 / 6 TYR A 265
ASP A 233
ILE A 313
TYR A 315
 None
 1.19A 5ih0A-2hjvA:
undetectable		 5ih0A-2hjvA:
21.38