SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hkr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CC8_A_RBFA1067_1 (VNG1446H)	2hkr	AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT (Alcaligenes faecalis)	3 / 3	PHE D 152 VAL D 158 TRP D 160	None None TRQ D 109 ( 3.4A)	0.83A	2cc8A-2hkrD: undetectable	2cc8A-2hkrD: 16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CCB_A_RBFA1067_1 (VNG1446H)	2hkr	AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT (Alcaligenes faecalis)	3 / 3	PHE D 152 VAL D 158 TRP D 160	None None TRQ D 109 ( 3.4A)	0.84A	2ccbA-2hkrD: undetectable	2ccbA-2hkrD: 16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VX9_A_RBFA1064_1 (DODECIN)	2hkr	AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT (Alcaligenes faecalis)	3 / 3	PHE D 152 VAL D 158 TRP D 160	None None TRQ D 109 ( 3.4A)	0.83A	2vx9A-2hkrD: undetectable	2vx9A-2hkrD: 11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2hkr	AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT (Alcaligenes faecalis)	3 / 3	ASP D 76 ASN D 73 PHE D 86	None	0.79A	5dsgB-2hkrD: undetectable	5dsgB-2hkrD: 14.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CC8_A_RBFA1067_1","VNG1446H","2hkr","AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT","Alcaligenes faecalis",3,"PHE D 152;VAL D 158;TRP D 160","None;None;TRQ D 109 ( 3.4A)","0.83A","2cc8A-2hkrD:undetectable","2cc8A-2hkrD:16.00"],["2CCB_A_RBFA1067_1","VNG1446H","2hkr","AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT","Alcaligenes faecalis",3,"PHE D 152;VAL D 158;TRP D 160","None;None;TRQ D 109 ( 3.4A)","0.84A","2ccbA-2hkrD:undetectable","2ccbA-2hkrD:16.00"],["2VX9_A_RBFA1064_1","DODECIN","2hkr","AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT","Alcaligenes faecalis",3,"PHE D 152;VAL D 158;TRP D 160","None;None;TRQ D 109 ( 3.4A)","0.83A","2vx9A-2hkrD:undetectable","2vx9A-2hkrD:11.48"],["5DSG_B_0HKB1201_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","2hkr","AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT","Alcaligenes faecalis",3,"ASP D  76;ASN D  73;PHE D  86","None","0.79A","5dsgB-2hkrD:undetectable","5dsgB-2hkrD:14.91"]]