SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_F_Z80F401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	2hl7	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH (Pseudomonas aeruginosa)	5 / 10	ILE A 61 ILE A 48 PHE A 16 ASP A 43 ILE A 33	None	1.24A	5lg3F-2hl7A: undetectable	5lg3F-2hl7A: 13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_G_Z80G401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	2hl7	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH (Pseudomonas aeruginosa)	5 / 10	ILE A 61 ILE A 48 PHE A 16 ASP A 43 ILE A 33	None	1.23A	5lg3G-2hl7A: undetectable	5lg3G-2hl7A: 13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_H_Z80H401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	2hl7	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH (Pseudomonas aeruginosa)	5 / 10	ILE A 61 ILE A 48 PHE A 16 ASP A 43 ILE A 33	None	1.18A	5lg3H-2hl7A: undetectable	5lg3H-2hl7A: 13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_J_Z80J401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	2hl7	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH (Pseudomonas aeruginosa)	5 / 12	ILE A 61 ILE A 48 PHE A 16 ASP A 43 ILE A 33	None	1.21A	5lg3J-2hl7A: undetectable	5lg3J-2hl7A: 13.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5LG3_F_Z80F401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","2hl7","CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH","Pseudomonas aeruginosa",5,"ILE A  61;ILE A  48;PHE A  16;ASP A  43;ILE A  33","None","1.24A","5lg3F-2hl7A:undetectable","5lg3F-2hl7A:13.65"],["5LG3_G_Z80G401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","2hl7","CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH","Pseudomonas aeruginosa",5,"ILE A  61;ILE A  48;PHE A  16;ASP A  43;ILE A  33","None","1.23A","5lg3G-2hl7A:undetectable","5lg3G-2hl7A:13.65"],["5LG3_H_Z80H401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","2hl7","CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH","Pseudomonas aeruginosa",5,"ILE A  61;ILE A  48;PHE A  16;ASP A  43;ILE A  33","None","1.18A","5lg3H-2hl7A:undetectable","5lg3H-2hl7A:13.65"],["5LG3_J_Z80J401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","2hl7","CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH","Pseudomonas aeruginosa",5,"ILE A  61;ILE A  48;PHE A  16;ASP A  43;ILE A  33","None","1.21A","5lg3J-2hl7A:undetectable","5lg3J-2hl7A:13.65"]]