SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 VAL A  27
GLY A  28
ASP A  53
ALA A  98
ILE A 119
 None
 0.79A 1cetA-2hlpA:
38.1		 1cetA-2hlpA:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 VAL A  27
GLY A  28
ASP A  53
ILE A  54
ALA A  98
 None
 0.74A 1cetA-2hlpA:
38.1		 1cetA-2hlpA:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 VAL A  27
GLY A  28
ASP A  53
TYR A  85
ALA A  98
 None
 0.56A 1cetA-2hlpA:
38.1		 1cetA-2hlpA:
31.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 8 ILE A 134
MET A 257
VAL A 142
LEU A 293
 None
 0.97A 1dzmA-2hlpA:
undetectable		 1dzmA-2hlpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_B_BZMB600_0
(ODORANT-BINDING
PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 ILE A 134
MET A 257
ASN A 146
GLY A 297
LEU A 293
 None
 1.14A 1dzmB-2hlpA:
0.0		 1dzmB-2hlpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_B_BZMB600_0
(ODORANT-BINDING
PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 ILE A 134
MET A 257
VAL A 142
ASN A 146
LEU A 293
 None
 1.31A 1dzmB-2hlpA:
0.0		 1dzmB-2hlpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.13A 1gtnB-2hlpA:
undetectable
1gtnC-2hlpA:
undetectable		 1gtnB-2hlpA:
14.62
1gtnC-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 11 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 1gtnM-2hlpA:
undetectable
1gtnN-2hlpA:
undetectable		 1gtnM-2hlpA:
14.62
1gtnN-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.09A 1gtnO-2hlpA:
undetectable
1gtnP-2hlpA:
undetectable		 1gtnO-2hlpA:
14.62
1gtnP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.14A 1gtnQ-2hlpA:
undetectable
1gtnR-2hlpA:
undetectable		 1gtnQ-2hlpA:
14.62
1gtnR-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.10A 1gtnU-2hlpA:
undetectable
1gtnV-2hlpA:
undetectable		 1gtnU-2hlpA:
14.62
1gtnV-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 GLY A 162
PHE A 163
SER A 169
ILE A 161
LEU A 293
 None
 1.08A 1lhuA-2hlpA:
undetectable		 1lhuA-2hlpA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 GLY A 249
GLY A 253
GLY A 164
GLY A 165
ASP A 168
 None
 1.00A 1mxdA-2hlpA:
undetectable		 1mxdA-2hlpA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 11 GLY A 249
GLY A 253
GLY A 164
GLY A 165
ASP A 168
 None
 0.96A 1mxgA-2hlpA:
undetectable		 1mxgA-2hlpA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 11 ARG A 171
THR A 246
GLY A 244
GLU A 241
MET A 237
 None
 1.36A 1odiA-2hlpA:
2.4		 1odiA-2hlpA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 11 ARG A 171
THR A 246
GLY A 244
GLU A 241
MET A 237
 None
 1.33A 1odiC-2hlpA:
2.0		 1odiC-2hlpA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 11 ARG A 171
THR A 246
GLY A 244
GLU A 241
MET A 237
 None
 1.33A 1odiE-2hlpA:
undetectable		 1odiE-2hlpA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 11 ARG A 171
THR A 246
GLY A 244
GLU A 241
MET A 237
 None
 1.37A 1odiF-2hlpA:
undetectable		 1odiF-2hlpA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		3 / 3 SER A  91
GLY A  90
ARG A  79
 None
 0.55A 1t9wA-2hlpA:
undetectable		 1t9wA-2hlpA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 1utdT-2hlpA:
undetectable
1utdU-2hlpA:
undetectable		 1utdT-2hlpA:
14.62
1utdU-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 THR A 138
GLY A 164
GLY A 165
ASP A 143
SER A 272
 None
 1.15A 1wg8A-2hlpA:
5.6		 1wg8A-2hlpA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 6 GLU A 178
TYR A 174
ASP A 238
ARG A 242
 None
 1.46A 2a3bB-2hlpA:
undetectable		 2a3bB-2hlpA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		3 / 3 VAL A 298
VAL A 160
ASP A 168
 None
 0.71A 2fumD-2hlpA:
undetectable		 2fumD-2hlpA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 7 GLY A 189
GLY A 193
GLN A 199
PHE A 203
 None
 0.94A 2qwxA-2hlpA:
5.0
2qwxB-2hlpA:
5.0		 2qwxA-2hlpA:
22.04
2qwxB-2hlpA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 ILE A  45
ASN A 131
ILE A 261
ALA A 260
THR A 265
 None
 1.16A 3a50A-2hlpA:
undetectable		 3a50A-2hlpA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 ILE A  45
ASN A 131
ILE A 261
ALA A 260
THR A 265
 None
 1.08A 3a51E-2hlpA:
undetectable		 3a51E-2hlpA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 5 VAL A  93
VAL A  94
GLN A 124
PHE A 163
 None
 1.37A 3bjwH-2hlpA:
undetectable		 3bjwH-2hlpA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 5 VAL A  93
VAL A  94
GLN A 124
PHE A 163
 None
 1.34A 3bjwB-2hlpA:
undetectable		 3bjwB-2hlpA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 LEU A 136
ALA A  36
VAL A  26
ILE A  45
VAL A  95
 None
 1.08A 3gguA-2hlpA:
undetectable		 3gguA-2hlpA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 7 LEU A 293
ARG A 267
THR A 265
ALA A 260
 None
 1.29A 3mbgA-2hlpA:
undetectable
3mbgB-2hlpA:
undetectable		 3mbgA-2hlpA:
17.59
3mbgB-2hlpA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 8 ALA A 255
ASN A  39
ALA A  41
THR A  76
 None
 1.07A 3t3sE-2hlpA:
undetectable		 3t3sE-2hlpA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		3 / 3 SER A 139
ASP A  53
ASP A  54
 None
 0.83A 3uj7A-2hlpA:
3.6		 3uj7A-2hlpA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 8 PHE A 163
GLY A 162
GLY A  33
ASN A  39
 None
 0.92A 3v3nB-2hlpA:
4.0		 3v3nB-2hlpA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 8 PHE A 163
GLY A 162
GLY A  33
ASN A  39
 None
 0.93A 3v3nC-2hlpA:
2.3		 3v3nC-2hlpA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		3 / 3 GLU A 151
TYR A 326
SER A 330
 None
 1.01A 4at0A-2hlpA:
2.9		 4at0A-2hlpA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		3 / 3 SER A 139
ASP A  53
ASP A  54
 None
 0.73A 4mwzA-2hlpA:
6.0		 4mwzA-2hlpA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 9 ASP A  53
TYR A  85
ALA A  98
ILE A 119
ILE A 123
 None
 0.66A 4oknB-2hlpA:
39.9		 4oknB-2hlpA:
34.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		4 / 6 ASP A 143
ALA A 318
LYS A 321
THR A 285
 None
 1.44A 4w5qA-2hlpA:
undetectable		 4w5qA-2hlpA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 GLY A 165
LEU A 314
GLY A 222
LEU A 229
THR A 190
 None
 1.15A 4ze2A-2hlpA:
undetectable		 4ze2A-2hlpA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.16A 5eeuF-2hlpA:
undetectable
5eeuG-2hlpA:
undetectable		 5eeuF-2hlpA:
14.62
5eeuG-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.14A 5eeuI-2hlpA:
undetectable
5eeuJ-2hlpA:
undetectable		 5eeuI-2hlpA:
14.62
5eeuJ-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 5eeuO-2hlpA:
undetectable
5eeuP-2hlpA:
undetectable		 5eeuO-2hlpA:
14.62
5eeuP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.16A 5eevF-2hlpA:
undetectable
5eevG-2hlpA:
undetectable		 5eevF-2hlpA:
14.62
5eevG-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.14A 5eevI-2hlpA:
undetectable
5eevJ-2hlpA:
undetectable		 5eevI-2hlpA:
14.62
5eevJ-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 5eevO-2hlpA:
undetectable
5eevP-2hlpA:
undetectable		 5eevO-2hlpA:
14.62
5eevP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.15A 5eewF-2hlpA:
undetectable
5eewG-2hlpA:
undetectable		 5eewF-2hlpA:
14.62
5eewG-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.14A 5eewI-2hlpA:
undetectable
5eewJ-2hlpA:
undetectable		 5eewI-2hlpA:
14.62
5eewJ-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 5eewO-2hlpA:
undetectable
5eewP-2hlpA:
undetectable		 5eewO-2hlpA:
14.62
5eewP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.15A 5eexF-2hlpA:
undetectable
5eexG-2hlpA:
undetectable		 5eexF-2hlpA:
14.62
5eexG-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 5eexO-2hlpA:
undetectable
5eexP-2hlpA:
undetectable		 5eexO-2hlpA:
14.62
5eexP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.15A 5eeyF-2hlpA:
undetectable
5eeyG-2hlpA:
undetectable		 5eeyF-2hlpA:
14.62
5eeyG-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.15A 5eeyO-2hlpA:
undetectable
5eeyP-2hlpA:
undetectable		 5eeyO-2hlpA:
14.62
5eeyP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.15A 5eezF-2hlpA:
undetectable
5eezG-2hlpA:
undetectable		 5eezF-2hlpA:
14.62
5eezG-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.16A 5eezO-2hlpA:
undetectable
5eezP-2hlpA:
undetectable		 5eezO-2hlpA:
14.62
5eezP-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.15A 5ef0F-2hlpA:
undetectable
5ef0G-2hlpA:
undetectable		 5ef0F-2hlpA:
14.62
5ef0G-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.15A 5ef0O-2hlpA:
undetectable
5ef0P-2hlpA:
undetectable		 5ef0O-2hlpA:
14.62
5ef0P-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.14A 5ef1F-2hlpA:
undetectable
5ef1G-2hlpA:
undetectable		 5ef1F-2hlpA:
14.62
5ef1G-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.15A 5ef1O-2hlpA:
undetectable
5ef1P-2hlpA:
undetectable		 5ef1O-2hlpA:
14.62
5ef1P-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.14A 5ef2F-2hlpA:
undetectable
5ef2G-2hlpA:
undetectable		 5ef2F-2hlpA:
14.62
5ef2G-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.15A 5ef2O-2hlpA:
undetectable
5ef2P-2hlpA:
undetectable		 5ef2O-2hlpA:
14.62
5ef2P-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 ALA A 251
GLY A  28
ALA A  36
THR A 138
THR A  97
 None
 1.14A 5ef3F-2hlpA:
undetectable
5ef3G-2hlpA:
undetectable		 5ef3F-2hlpA:
14.62
5ef3G-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 10 GLY A  28
ALA A  36
THR A 138
THR A  97
ALA A 251
 None
 1.15A 5ef3O-2hlpA:
undetectable
5ef3P-2hlpA:
undetectable		 5ef3O-2hlpA:
14.62
5ef3P-2hlpA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 ASP A 122
PRO A  54
THR A  59
GLN A  62
GLY A  28
 None
 1.21A 5hfjC-2hlpA:
undetectable		 5hfjC-2hlpA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 GLY A  61
LEU A  42
ASN A  39
ASP A  73
ASP A  65
 None
 1.37A 5yn6A-2hlpA:
undetectable		 5yn6A-2hlpA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 GLY A  61
LEU A  42
ASN A  39
ASP A  73
ASP A  65
 None
 1.33A 5yniA-2hlpA:
4.0		 5yniA-2hlpA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 GLY A  30
GLY A  33
VAL A  26
VAL A 254
PRO A 250
 None
 1.12A 6gneA-2hlpA:
5.2		 6gneA-2hlpA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 2hlp MALATE DEHYDROGENASE
(Haloarcula
marismortui) 		5 / 12 GLY A  30
GLY A  33
VAL A  26
VAL A 254
PRO A 250
 None
 1.12A 6gneB-2hlpA:
5.1		 6gneB-2hlpA:
21.28