SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2hna PROTEIN MIOC
(Escherichia
coli) 		4 / 8 THR A  56
SER A  54
GLU A 106
ALA A  87
 None
 0.89A 2v32A-2hnaA:
undetectable
2v32B-2hnaA:
undetectable		 2v32A-2hnaA:
20.51
2v32B-2hnaA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2hna PROTEIN MIOC
(Escherichia
coli) 		5 / 12 GLY A  38
GLY A   9
SER A  10
LEU A  40
LEU A  36
 None
 1.09A 5c0oH-2hnaA:
undetectable		 5c0oH-2hnaA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 2hna PROTEIN MIOC
(Escherichia
coli) 		5 / 12 LEU A  66
THR A  56
ILE A  90
GLY A  89
ILE A  88
 None
 1.04A 5ifuA-2hnaA:
4.9		 5ifuA-2hnaA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2hna PROTEIN MIOC
(Escherichia
coli) 		3 / 3 LEU A 109
THR A  56
ASN A  65
 None
 0.61A 6baaE-2hnaA:
undetectable		 6baaE-2hnaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2hna PROTEIN MIOC
(Escherichia
coli) 		3 / 3 LEU A 109
THR A  56
ASN A  65
 None
 0.61A 6baaF-2hnaA:
undetectable		 6baaF-2hnaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2hna PROTEIN MIOC
(Escherichia
coli) 		3 / 3 LEU A 109
THR A  56
ASN A  65
 None
 0.62A 6baaG-2hnaA:
undetectable		 6baaG-2hnaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2hna PROTEIN MIOC
(Escherichia
coli) 		3 / 3 LEU A 109
THR A  56
ASN A  65
 None
 0.62A 6baaH-2hnaA:
undetectable		 6baaH-2hnaA:
6.57