SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 THR A 111
VAL A  69
THR A  35
VAL A  37
 None
 1.00A 1dz9A-2hngA:
undetectable		 1dz9A-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A  17
THR A 111
THR A  35
VAL A  37
 None
 0.74A 1dz9A-2hngA:
undetectable		 1dz9A-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A  17
THR A 111
THR A  35
VAL A  37
 None
 0.70A 1o76B-2hngA:
undetectable		 1o76B-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 VAL A  57
VAL A  85
CYH A 103
ARG A 101
 None
 1.11A 1t46A-2hngA:
undetectable		 1t46A-2hngA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 THR A 111
VAL A  69
THR A  35
VAL A  37
 None
 1.00A 1uyuA-2hngA:
undetectable		 1uyuA-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A  17
THR A 111
THR A  35
VAL A  37
 None
 0.77A 1uyuA-2hngA:
undetectable		 1uyuA-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 THR A 111
VAL A  69
THR A  35
VAL A  37
 None
 1.11A 1uyuB-2hngA:
undetectable		 1uyuB-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A  17
THR A 111
THR A  35
VAL A  37
 None
 0.83A 1uyuB-2hngA:
undetectable		 1uyuB-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A  17
THR A 111
THR A  35
VAL A  37
 None
 0.74A 2a1mB-2hngA:
undetectable		 2a1mB-2hngA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 TYR A  17
THR A 111
THR A  35
VAL A  37
 None
 0.83A 3fwiA-2hngA:
undetectable		 3fwiA-2hngA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 PHE A  65
ILE A  70
PHE A 128
ASN A 108
 None
 1.48A 4o7gB-2hngA:
undetectable		 4o7gB-2hngA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 LEU A   7
ASN A  78
LEU A  91
ILE A  58
 None
 1.02A 4ok1A-2hngA:
undetectable		 4ok1A-2hngA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LEU A  59
SER A  60
PHE A  61
HIS A  18
 None
 1.19A 5om3A-2hngA:
undetectable
5om3B-2hngA:
undetectable		 5om3A-2hngA:
19.67
5om3B-2hngA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 TYR A 112
ALA A 118
LEU A 119
 None
 0.55A 6ag0C-2hngA:
undetectable		 6ag0C-2hngA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2hng HYPOTHETICAL PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 GLN A  76
VAL A  77
PRO A 102
THR A  53
 None
 1.34A 6cduA-2hngA:
undetectable
6cduB-2hngA:
undetectable		 6cduA-2hngA:
19.06
6cduB-2hngA:
19.06