SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hnz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.72A 1fk9A-2hnzA:
41.7		 1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
 1.47A 1fk9A-2hnzA:
41.7		 1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LYS A 101
LYS A 103
VAL A 106
VAL A 179
GLY A 190
 None
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
 1.09A 1fk9A-2hnzA:
41.7		 1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LYS A 101
LYS A 103
VAL A 179
TYR A 181
GLY A 190
 None
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
 1.19A 1fk9A-2hnzA:
41.7		 1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.67A 1fkoA-2hnzA:
36.4		 1fkoA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.20A 1fkoA-2hnzA:
36.4		 1fkoA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 11 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.33A 1fkpA-2hnzA:
35.9		 1fkpA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 11 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.54A 1fkpA-2hnzA:
35.9		 1fkpA-2hnzA:
99.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 ASP A 511
ASN A 363
ASP A 364
TRP A 426
 None
 1.35A 1hpkA-2hnzA:
undetectable		 1hpkA-2hnzA:
9.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.73A 1ikvA-2hnzA:
37.5		 1ikvA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 9 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.46A 1ikvA-2hnzA:
37.5		 1ikvA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.76A 1ikwA-2hnzA:
37.6		 1ikwA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.47A 1ikwA-2hnzA:
37.6		 1ikwA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 11 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.65A 1jkhA-2hnzA:
35.7
1jkhB-2hnzA:
13.9		 1jkhA-2hnzA:
99.07
1jkhB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 11 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
 1.26A 1jkhA-2hnzA:
35.7
1jkhB-2hnzA:
13.9		 1jkhA-2hnzA:
99.07
1jkhB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 8 LEU A 100
VAL A 106
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.52A 1jlbA-2hnzA:
35.1		 1jlbA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 100
TYR A 181
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.66A 1jlfA-2hnzA:
35.4
1jlfB-2hnzA:
20.8		 1jlfA-2hnzA:
99.07
1jlfB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 8 LEU A 100
VAL A 106
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 0.55A 1jlfA-2hnzA:
35.4
1jlfB-2hnzA:
20.8		 1jlfA-2hnzA:
99.07
1jlfB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 11 LEU A 100
LYS A 102
PRO A 226
PHE A 227
LEU A 234
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 1.27A 1klmA-2hnzA:
35.7		 1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 11 LEU A 100
LYS A 102
TYR A 181
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 1.33A 1klmA-2hnzA:
35.7		 1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 11 LEU A 100
LYS A 102
VAL A 106
TYR A 181
TYR A 188
PRO A 226
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.95A 1klmA-2hnzA:
35.7		 1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 11 LEU A 100
LYS A 102
VAL A 106
TYR A 181
TYR A 188
PRO A 226
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.93A 1klmA-2hnzA:
35.7		 1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.73A 1lw0A-2hnzA:
41.4		 1lw0A-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
 1.49A 1lw0A-2hnzA:
41.4		 1lw0A-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		11 / 11 PRO A  95
LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.72A 1lwcA-2hnzA:
41.5		 1lwcA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 7 LEU A 100
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 0.33A 1lweA-2hnzA:
34.2		 1lweA-2hnzA:
98.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.55A 1lwfA-2hnzA:
35.2		 1lwfA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 9 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.24A 1lwfA-2hnzA:
35.2		 1lwfA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 9 VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
 PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
 1.49A 1lwfA-2hnzA:
35.2		 1lwfA-2hnzA:
98.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 12 LEU A 368
GLY A 352
TYR A 354
ILE A 329
THR A 386
 None
 0.84A 1p91B-2hnzA:
undetectable		 1p91B-2hnzA:
19.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.77A 1s1uA-2hnzA:
41.1		 1s1uA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LYS A 103
VAL A 179
TYR A 181
GLY A 190
TYR A 318
 None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.35A 1s1uA-2hnzA:
41.1		 1s1uA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 8 LEU A 100
VAL A 106
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.57A 1s1xA-2hnzA:
35.7		 1s1xA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 10 LEU A 100
LYS A 101
PRO A 226
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 1.14A 1sv5A-2hnzA:
35.6		 1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 10 LEU A 100
LYS A 101
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.88A 1sv5A-2hnzA:
35.6		 1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
LYS A 101
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
 0.99A 1sv5A-2hnzA:
35.6		 1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 TYR A 181
PRO A 225
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.96A 1sv5A-2hnzA:
35.6		 1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 ASP A 110
TYR A 183
MET A 184
ASP A 185
 None
 0.74A 1t03A-2hnzA:
34.5		 1t03A-2hnzA:
97.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.78A 1v54A-2hnzA:
undetectable
1v54J-2hnzA:
undetectable		 1v54A-2hnzA:
19.77
1v54J-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.72A 1v55A-2hnzA:
undetectable
1v55J-2hnzA:
undetectable		 1v55A-2hnzA:
19.77
1v55J-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.76A 1v55N-2hnzA:
2.4
1v55W-2hnzA:
undetectable		 1v55N-2hnzA:
19.77
1v55W-2hnzA:
6.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.69A 1vrtA-2hnzA:
41.1		 1vrtA-2hnzA:
99.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.78A 2dyrA-2hnzA:
undetectable
2dyrJ-2hnzA:
undetectable		 2dyrA-2hnzA:
19.77
2dyrJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.79A 2dysA-2hnzA:
2.2
2dysJ-2hnzA:
undetectable		 2dysA-2hnzA:
19.77
2dysJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.80A 2dysN-2hnzA:
2.2
2dysW-2hnzA:
undetectable		 2dysN-2hnzA:
19.77
2dysW-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.76A 2eijA-2hnzA:
undetectable
2eijJ-2hnzA:
undetectable		 2eijA-2hnzA:
19.77
2eijJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.79A 2eilA-2hnzA:
undetectable
2eilJ-2hnzA:
undetectable		 2eilA-2hnzA:
19.77
2eilJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.82A 2einA-2hnzA:
2.6
2einJ-2hnzA:
undetectable		 2einA-2hnzA:
19.77
2einJ-2hnzA:
6.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.71A 2hndA-2hnzA:
42.3		 2hndA-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.77A 2hnyA-2hnzA:
42.3		 2hnyA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.82A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.92A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.79A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.90A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.74A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.90A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.73A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.87A 2zd1A-2hnzA:
36.1		 2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 PRO A  95
PRO A 226
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 1.24A 2ze2A-2hnzA:
35.3		 2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 PRO A  95
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.71A 2ze2A-2hnzA:
35.3		 2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 PRO A  95
VAL A 179
TYR A 181
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.80A 2ze2A-2hnzA:
35.3		 2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 TYR A 181
TYR A 188
PRO A 225
LEU A 234
TYR A 318
 PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.81A 2ze2A-2hnzA:
35.3		 2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.86A 2ze2A-2hnzA:
35.3		 2ze2A-2hnzA:
98.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.85A 2zxwA-2hnzA:
2.2
2zxwJ-2hnzA:
undetectable		 2zxwA-2hnzA:
19.77
2zxwJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.78A 3abkA-2hnzA:
2.1
3abkJ-2hnzA:
undetectable		 3abkA-2hnzA:
19.77
3abkJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.76A 3abmA-2hnzA:
2.2
3abmJ-2hnzA:
undetectable		 3abmA-2hnzA:
19.77
3abmJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.76A 3abmN-2hnzA:
undetectable
3abmW-2hnzA:
undetectable		 3abmN-2hnzA:
19.77
3abmW-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.77A 3ag3A-2hnzA:
2.5
3ag3J-2hnzA:
undetectable		 3ag3A-2hnzA:
19.77
3ag3J-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.79A 3asnA-2hnzA:
2.4
3asnJ-2hnzA:
undetectable		 3asnA-2hnzA:
19.77
3asnJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.77A 3asoA-2hnzA:
undetectable
3asoJ-2hnzA:
undetectable		 3asoA-2hnzA:
19.77
3asoJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.75A 3asoN-2hnzA:
1.9
3asoW-2hnzA:
undetectable		 3asoN-2hnzA:
19.77
3asoW-2hnzA:
6.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 11 LEU A 100
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 1.06A 3bgrA-2hnzA:
35.2
3bgrB-2hnzA:
14.1		 3bgrA-2hnzA:
98.13
3bgrB-2hnzA:
98.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 11 LEU A 100
VAL A 179
TYR A 188
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 1.08A 3bgrA-2hnzA:
35.2
3bgrB-2hnzA:
14.1		 3bgrA-2hnzA:
98.13
3bgrB-2hnzA:
98.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		3 / 3 THR A 216
GLU A 203
HIS A 198
 None
 0.79A 3g1uB-2hnzA:
undetectable		 3g1uB-2hnzA:
22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 9 LEU A 100
LYS A 103
TYR A 181
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 1.47A 3hvtA-2hnzA:
14.5		 3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 9 LEU A 100
LYS A 103
VAL A 106
TYR A 181
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.72A 3hvtA-2hnzA:
14.5		 3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 9 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 0.77A 3hvtA-2hnzA:
14.5		 3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 9 LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TRP A 229
 None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
 1.43A 3hvtA-2hnzA:
14.5		 3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.64A 3lp0A-2hnzA:
37.5		 3lp0A-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
 0.76A 3lp0A-2hnzA:
37.5		 3lp0A-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.75A 3lp1A-2hnzA:
37.9		 3lp1A-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 11 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.73A 3m8pA-2hnzA:
37.9
3m8pB-2hnzA:
14.4		 3m8pA-2hnzA:
99.26
3m8pB-2hnzA:
99.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 11 LYS A 103
VAL A 106
VAL A 179
PHE A 227
TYR A 318
 None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.90A 3m8pA-2hnzA:
37.9
3m8pB-2hnzA:
14.4		 3m8pA-2hnzA:
99.26
3m8pB-2hnzA:
99.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
GLY A 190
TRP A 229
LEU A 234
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.82A 3mecA-2hnzA:
38.1		 3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.69A 3mecA-2hnzA:
38.1		 3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
GLY A 190
LEU A 234
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.68A 3mecA-2hnzA:
38.1		 3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.54A 3mecA-2hnzA:
38.1		 3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LYS A 103
VAL A 106
VAL A 179
GLY A 190
PHE A 227
LEU A 234
PRO A 236
TYR A 318
 None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.93A 3mecA-2hnzA:
38.1		 3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 12 LYS A 103
VAL A 179
TYR A 181
GLY A 190
PRO A 236
TYR A 318
 None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 1.22A 3mecA-2hnzA:
38.1		 3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.66A 3medA-2hnzA:
38.1
3medB-2hnzA:
14.4		 3medA-2hnzA:
99.07
3medB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.50A 3medA-2hnzA:
38.1
3medB-2hnzA:
14.4		 3medA-2hnzA:
99.07
3medB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 12 VAL A 106
VAL A 179
GLY A 190
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.89A 3medA-2hnzA:
38.1
3medB-2hnzA:
14.4		 3medA-2hnzA:
99.07
3medB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 12 LEU A 100
LYS A 103
VAL A 179
TYR A 181
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.3A)
 1.34A 3meeA-2hnzA:
38.2		 3meeA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		10 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.67A 3meeA-2hnzA:
38.2		 3meeA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		10 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.65A 3meeA-2hnzA:
38.2		 3meeA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.72A 3megA-2hnzA:
38.1		 3megA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.69A 3megA-2hnzA:
38.1		 3megA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.73A 3qipA-2hnzA:
38.5		 3qipA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.83A 3qipA-2hnzA:
38.5		 3qipA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 12 LEU A 100
LYS A 103
TYR A 188
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 1.33A 3qlhA-2hnzA:
35.9		 3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.92A 3qlhA-2hnzA:
35.9		 3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 1.01A 3qlhA-2hnzA:
35.9		 3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.90A 3qlhA-2hnzA:
35.9		 3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.89A 3qlhA-2hnzA:
35.9		 3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 8 LEU A 100
LYS A 103
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.80A 3v81A-2hnzA:
35.6		 3v81A-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.66A 3v81C-2hnzA:
36.6		 3v81C-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 9 LEU A 100
LYS A 101
LYS A 103
VAL A 106
TYR A 181
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.82A 4b3oA-2hnzA:
34.0		 4b3oA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 9 LEU A 100
LYS A 101
LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
None
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 0.83A 4b3oA-2hnzA:
34.0		 4b3oA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 7 LEU A 100
LYS A 103
VAL A 106
TYR A 181
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.88A 4b3qA-2hnzA:
31.5		 4b3qA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 7 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.3A)
 0.87A 4b3qA-2hnzA:
31.5		 4b3qA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.81A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.96A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.76A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.92A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.80A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.89A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.77A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.85A 4g1qA-2hnzA:
36.1		 4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.82A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.91A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.80A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.90A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.71A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.85A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.71A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.84A 4iclA-2hnzA:
36.2		 4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.81A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.91A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.76A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.87A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.75A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.84A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.71A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.80A 4id5A-2hnzA:
36.1		 4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.76A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.86A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
 0.75A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
 0.85A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.67A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.78A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.67A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.77A 4idkA-2hnzA:
36.1		 4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.80A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.87A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.75A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.82A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.74A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.83A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.68A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.79A 4ifvA-2hnzA:
36.0		 4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.83A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.90A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.79A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.87A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.72A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.84A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.69A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.82A 4ifyA-2hnzA:
36.1		 4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.83A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.91A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.77A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.86A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.78A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.87A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.72A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.82A 4ig3A-2hnzA:
36.1		 4ig3A-2hnzA:
98.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A  34
CYH A  38
TYR A 144
PRO A 133
 None
 1.09A 4j7uD-2hnzA:
undetectable		 4j7uD-2hnzA:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 12 LEU A 100
LYS A 103
TYR A 188
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 1.06A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.78A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.89A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.78A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
PRO A 236
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.90A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 12 LEU A 100
VAL A 179
TYR A 188
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 1.26A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.70A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.82A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.70A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 236
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
 0.84A 4kfbA-2hnzA:
36.1		 4kfbA-2hnzA:
98.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 8 VAL A 531
LEU A 533
LEU A 429
TYR A 427
ILE A 521
 None
 1.21A 4lzrA-2hnzA:
1.4		 4lzrA-2hnzA:
13.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 9 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.77A 4puoA-2hnzA:
36.6		 4puoA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.67A 4puoC-2hnzA:
36.5		 4puoC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 8 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
 0.80A 4pwdA-2hnzA:
36.2		 4pwdA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.61A 4pwdC-2hnzA:
36.6		 4pwdC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.63A 4pwdC-2hnzA:
36.6		 4pwdC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 8 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
 0.72A 4q0bA-2hnzA:
36.0		 4q0bA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 8 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
 0.72A 4q0bA-2hnzA:
36.0		 4q0bA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 9 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.74A 4q0bC-2hnzA:
36.4		 4q0bC-2hnzA:
98.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 422
VAL A 365
LEU A 368
PHE A 389
 None
 0.97A 4r38B-2hnzA:
undetectable		 4r38B-2hnzA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 5 LEU A 517
ALA A 502
THR A 497
ILE A 495
 None
 0.95A 4xe3B-2hnzA:
undetectable		 4xe3B-2hnzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.75A 5b1aA-2hnzA:
2.3
5b1aJ-2hnzA:
undetectable		 5b1aA-2hnzA:
19.77
5b1aJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.78A 5b3sA-2hnzA:
2.3
5b3sJ-2hnzA:
undetectable		 5b3sA-2hnzA:
19.77
5b3sJ-2hnzA:
6.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.86A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.92A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.85A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.93A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PHE A 227
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.72A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.86A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PHE A 227
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.73A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.85A 5cymA-2hnzA:
35.9		 5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.83A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.91A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.84A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.94A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PHE A 227
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.72A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.80A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PHE A 227
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.76A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.82A 5cyqA-2hnzA:
35.9		 5cyqA-2hnzA:
98.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 9 ALA A 437
LEU A 491
GLY A 490
LYS A 530
GLU A 529
 None
None
PO4  A1300 ( 4.6A)
None
None
 1.20A 5dqfA-2hnzA:
undetectable		 5dqfA-2hnzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 4 LEU A 234
TYR A 319
PRO A  95
ILE A  94
 PC0  A 999 (-4.2A)
None
PC0  A 999 ( 4.9A)
None
 1.42A 5esgA-2hnzA:
undetectable		 5esgA-2hnzA:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 11 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.66A 5hbmA-2hnzA:
37.5		 5hbmA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 11 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.73A 5hbmA-2hnzA:
37.5		 5hbmA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 11 PRO A  95
LYS A 103
VAL A 106
VAL A 179
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.83A 5hbmA-2hnzA:
37.5		 5hbmA-2hnzA:
98.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.83A 5x1fA-2hnzA:
2.3
5x1fJ-2hnzA:
undetectable		 5x1fA-2hnzA:
19.77
5x1fJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.82A 5xdxA-2hnzA:
2.1
5xdxJ-2hnzA:
undetectable		 5xdxA-2hnzA:
19.77
5xdxJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 12 ILE A 522
GLN A 524
ILE A 495
LEU A 533
ILE A 505
 None
 1.08A 5y2tB-2hnzA:
undetectable		 5y2tB-2hnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.77A 5zcpA-2hnzA:
2.1
5zcpJ-2hnzA:
undetectable		 5zcpA-2hnzA:
19.77
5zcpJ-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 8 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.74A 5zcpN-2hnzA:
2.2
5zcpW-2hnzA:
undetectable		 5zcpN-2hnzA:
19.77
5zcpW-2hnzA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 7 LEU A 109
MET A 164
THR A 165
LEU A 168
 None
 0.74A 5zcqA-2hnzA:
2.2
5zcqJ-2hnzA:
undetectable		 5zcqA-2hnzA:
19.77
5zcqJ-2hnzA:
6.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.81A 6bsgA-2hnzA:
35.8		 6bsgA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.83A 6bsgA-2hnzA:
35.8		 6bsgA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		5 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
 1.46A 6bsgA-2hnzA:
35.8		 6bsgA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
LYS A 103
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.75A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
LYS A 103
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.89A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 10 LEU A 100
LYS A 103
VAL A 106
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.81A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 10 LEU A 100
LYS A 103
VAL A 106
TYR A 188
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 0.86A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 10 LEU A 100
VAL A 106
VAL A 179
GLY A 190
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.64A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		6 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 188
GLY A 190
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
 0.72A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.58A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.74A 6bsiA-2hnzA:
35.9		 6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		7 / 10 LEU A 100
LYS A 103
VAL A 106
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.97A 6bsjA-2hnzA:
35.5		 6bsjA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.66A 6bsjA-2hnzA:
35.5		 6bsjA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.72A 6bsjA-2hnzA:
35.5		 6bsjA-2hnzA:
98.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		3 / 3 SER A 513
SER A 515
ALA A 502
 None
 0.70A 6dwnC-2hnzA:
undetectable		 6dwnC-2hnzA:
10.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.80A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.84A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.80A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.85A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.68A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.76A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.68A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.76A 6eliA-2hnzA:
36.5		 6eliA-2hnzA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 5 ASP A 511
ASP A 364
GLN A 512
LYS A 331
 None
 1.21A 6g31H-2hnzA:
undetectable		 6g31H-2hnzA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
(Human
immunodeficiency
virus
1) 		4 / 6 ASP A 511
ASP A 364
GLN A 512
LYS A 331
 None
 1.43A 6g31L-2hnzA:
undetectable		 6g31L-2hnzA:
10.00