SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ho0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ho0 REPRESSOR PROTEIN
CI101-229DM-K192A
(Escherichia
coli) 		4 / 7 LYS A 193
LEU A 203
GLN A 204
PHE A 202
 None
 1.09A 2dysP-2ho0A:
undetectable
2dysW-2ho0A:
undetectable		 2dysP-2ho0A:
19.11
2dysW-2ho0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ho0 REPRESSOR PROTEIN
CI101-229DM-K192A
(Escherichia
coli) 		4 / 7 LYS A 193
LEU A 203
GLN A 204
PHE A 202
 None
 1.02A 2eijP-2ho0A:
undetectable
2eijW-2ho0A:
undetectable		 2eijP-2ho0A:
19.11
2eijW-2ho0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ho0 REPRESSOR PROTEIN
CI101-229DM-K192A
(Escherichia
coli) 		4 / 7 LYS A 193
LEU A 203
GLN A 204
PHE A 202
 None
 1.05A 2eimC-2ho0A:
undetectable
2eimJ-2ho0A:
undetectable		 2eimC-2ho0A:
19.11
2eimJ-2ho0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 2ho0 REPRESSOR PROTEIN
CI101-229DM-K192A
(Escherichia
coli) 		5 / 12 LEU A 194
GLY A 177
VAL A 225
MET A 150
THR A 158
 None
 1.48A 2q7lA-2ho0A:
undetectable		 2q7lA-2ho0A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ho0 REPRESSOR PROTEIN
CI101-229DM-K192A
(Escherichia
coli) 		3 / 3 GLN A 229
TRP A 142
VAL A 105
 None
 1.14A 6auuA-2ho0A:
undetectable		 6auuA-2ho0A:
17.01