SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ho9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LZR_A_LOCA201_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	4 / 8	VAL A 102 LEU A 71 TYR A 29 ILE A 31	None	0.88A	4lzrA-2ho9A: undetectable	4lzrA-2ho9A: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTW_A_DB8A1101_2 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	3 / 3	LEU A 20 LEU A 150 ASN A 92	None	0.59A	4otwA-2ho9A: undetectable	4otwA-2ho9A: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	4 / 7	GLY A 57 VAL A 88 ILE A 100 VAL A 101	None	0.68A	5ik1A-2ho9A: undetectable	5ik1A-2ho9A: 18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y1Y_A_HNQA201_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	4 / 8	VAL A 102 LEU A 71 TYR A 29 ILE A 31	None	0.89A	5y1yA-2ho9A: undetectable	5y1yA-2ho9A: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DIL_B_TPVB201_1 (HIV-1 PROTEASE)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	5 / 12	LEU A 20 GLY A 104 GLY A 41 VAL A 36 ILE A 89	None	0.88A	6dilB-2ho9A: undetectable	6dilB-2ho9A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_A_SAMA501_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	6 / 12	LEU A 20 ILE A 31 GLY A 30 ILE A 39 VAL A 87 ILE A 89	None	1.09A	6emuA-2ho9A: undetectable	6emuA-2ho9A: 24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_B_SAMB301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	5 / 12	LEU A 20 ILE A 31 GLY A 30 VAL A 87 ILE A 89	None	0.97A	6emuB-2ho9A: undetectable	6emuB-2ho9A: 24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_C_SAMC301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	2ho9	CHEMOTAXIS PROTEIN CHEW (Escherichia coli)	5 / 12	LEU A 20 ILE A 31 GLY A 30 VAL A 87 ILE A 89	None	1.00A	6emuC-2ho9A: undetectable	6emuC-2ho9A: 24.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4LZR_A_LOCA201_1","BROMODOMAIN-CONTAINING PROTEIN 4","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",4,"VAL A 102;LEU A  71;TYR A  29;ILE A  31","None","0.88A","4lzrA-2ho9A:undetectable","4lzrA-2ho9A:21.74"],["4OTW_A_DB8A1101_2","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",3,"LEU A  20;LEU A 150;ASN A  92","None","0.59A","4otwA-2ho9A:undetectable","4otwA-2ho9A:21.47"],["5IK1_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",4,"GLY A  57;VAL A  88;ILE A 100;VAL A 101","None","0.68A","5ik1A-2ho9A:undetectable","5ik1A-2ho9A:18.72"],["5Y1Y_A_HNQA201_1","BROMODOMAIN-CONTAINING PROTEIN 4","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",4,"VAL A 102;LEU A  71;TYR A  29;ILE A  31","None","0.89A","5y1yA-2ho9A:undetectable","5y1yA-2ho9A:19.32"],["6DIL_B_TPVB201_1","HIV-1 PROTEASE","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",5,"LEU A  20;GLY A 104;GLY A  41;VAL A  36;ILE A  89","None","0.88A","6dilB-2ho9A:undetectable","6dilB-2ho9A:20.00"],["6EMU_A_SAMA501_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",6,"LEU A  20;ILE A  31;GLY A  30;ILE A  39;VAL A  87;ILE A  89","None","1.09A","6emuA-2ho9A:undetectable","6emuA-2ho9A:24.15"],["6EMU_B_SAMB301_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",5,"LEU A  20;ILE A  31;GLY A  30;VAL A  87;ILE A  89","None","0.97A","6emuB-2ho9A:undetectable","6emuB-2ho9A:24.15"],["6EMU_C_SAMC301_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","2ho9","CHEMOTAXIS PROTEIN CHEW","Escherichia coli",5,"LEU A  20;ILE A  31;GLY A  30;VAL A  87;ILE A  89","None","1.00A","6emuC-2ho9A:undetectable","6emuC-2ho9A:24.15"]]